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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Novel Anti-Viral Therapy: Drugs that Block HIV Entry at Different Target Sites
- Source: Mini Reviews in Medicinal Chemistry, Volume 6, Issue 5, May 2006, p. 557 - 562
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- 01 May 2006
Abstract
Drugs that block the entry of human immunodeficiency virus type 1 (HIV-1) into host cells abrogate the establishment of a productive infection and should ideally diminish the chances of HIV-1 developing resistance. This review will give an overview of the mechanism by which the envelope glycoprotein mediates HIV-1 entry and will summarize current drug developments.
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