Full text loading...
- ISSN: 1389-5575
- E-ISSN: 1875-5607
-
Monoamine Oxidases: to Inhibit or Not to Inhibit
- Source: Mini Reviews in Medicinal Chemistry, Volume 3, Issue 2, Mar 2003, p. 129 - 136
-
- 01 Mar 2003
Abstract
Monoamine oxidase (MAO) inhibitors were developed as antidepressants but many drugs, including the novel oxazolidinone antibacterial agents, share similar molecular properties and have MAO inhibitory activity. Factors important for binding antidepressants and modifications to decrease binding of oxazolidinones to avoid undesirable vascular effects are discussed.
© Bentham Science Publishers