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2000
Volume 24, Issue 9
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

Quinoxaline derivatives have been incorporated into numerous marketed drugs used for the treatment of various diseases. Examples include glecaprevir (Mavyret), voxilaprevir (Vosevi), Balversa (L01EX16) (erdafitinib), carbadox, XK469R (NSC698215), and becampanel (AMP397). These quinoxaline derivatives exhibit a diverse range of pharmacological activities, including antibacterial, antitubercular, antiviral, anti-HIV, anti-inflammatory, antifungal, anticancer, antiproliferative, antitumor, kinase inhibition, antimicrobial, antioxidant, and analgesic effects. Recognizing the significance of these bioactive quinoxaline derivatives, researchers have dedicated their efforts to developing various synthetic methods for their production. This review aimed to compile the most recent findings on the synthesis and biological properties of quinoxaline derivatives from 2015 to 2023.

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/content/journals/mrmc/10.2174/0113895575264375231012115026
2024-05-01
2025-07-07
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  • Article Type:
    Review Article
Keyword(s): anticancer; antiviral; biological activity; compound; Quinoxaline; synthesis
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