Micro and Nanosystems - Volume 13, Issue 3, 2021

Background: Self-assembled drug delivery systems are of much interest since they can be produced by simple low cost and solvent-free procedures. Pharmacosomes are supramolecularstructured nanocarriers with benefits for drug stability and targeting delivery. Amphotericin B (AmB) still remains an important agent for the treatment of invasive mold infections, e.g invasive aspergillosis, although the challenge fo Read More

Aims: The administration of antitumor 5-Fluorouracil (5-FU) into the human body is generally accomplished via a central venous catheter that is prone to degradation when it comes in contact with bodily fluids or aggressive drugs such as 5-Fu. Therefore, degradation could be reduced by applying protective coatings onto the internal and/or external surfaces of the catheters. Objective: Graphene and silica materials could b Read More

Acne is a chronic disease associated with the pilosebaceous unit and is affected by Propionibacterium acnes bacteria. Approximately 95% of people worldwide suffer from acne in their life span with a higher prevalence among teenagers (esp. boys). Conventional strategies incorporating antibiotics, steroids, hormones, etc. are recommended orally, systemically, or topically, employed for the treatment of acne but with var Read More

Background: For higher-order multiplications, a huge number of adders or compressors are used to perform the addition of the partial products. Objective: Hence, the area and the propagation delay will increase. Researchers are trying to reduce the number of additions of partial products. Methods: In this paper, different modified compressors have been proposed and based on these compressors, 16x16-bit binary multiplie Read More

Background: A relatively narrow LSPR peak and a strong interband transition ranging around 800 nm make Al a strongly plasmonic active material. Usually, Al nanoparticles are preferred for UV-plasmonic as the SPR of small size Al nanoparticles is located in the deep UV-UV region of the optical spectrum. This paper focused on tuning the LSPR of Al nanostructure towards the infrared region by coating the Au layer. The proposed Read More

Aims: AA7076 is a well-defined alloy for its excellent physical and mechanical properties such as high strength, toughness, and low density. To meet the requirements of the automobile and aerospace industry, the properties of AA7076 alloy have to be improved by reinforcing nano-sized graphene amine particles. Objectives: The aim of this study is to synthesize and characterize the AA7076 alloy reinforced with graphene Read More

Background: Moxifloxacin is a BCS class I drug used in the treatment of bacterial conjunctivitis and keratitis. Despite its high water solubility, it possesses limited bioavailability due to anatomical and physiological constraints associated with the eyes, which require multiple administrations to achieve a therapeutic effect. Objective: In order to prolong drug release and to improve antibacterial efficacy for the treatment of bacte Read More

Background: HQ is used for hyper-pigmentation treatment using conventional creams and gels. These formulations show various disadvantages like poor skin permeation, allergic reactions, and repeated use and decreasing patient compliance. Objectives: The present work involved formulation, statistical optimization, and characterization of Nanostructured Lipid Carriers (NLCs) for efficient topical delivery of hydroquinone (HQ) f Read More

Aims: The semiconductor technology has a great impact on consistent growth in the Very-Large- Scale Integrated (VLSI) devices. The transistor size has been scaled down from micron to submicron and towards the nanometer regime in the past 30 years due to technological advancements. The most reliable solid-state device is Metal-Oxide-Semiconductor Field Effect Transistor (MOSFET) but this rapid decrease in the device dime Read More

Background: The current treatments of leishmaniosis are far from ideal since they require the administration of toxic and poorly tolerated drugs that still fail to treat the intracellular infection. Micro-particles are very promising drug carriers for leishmaniosis treatment, considering the involved parasites’ life cycle and the pharmacokinetics of micro-particles. Objective: The aim of this study is to develop a novel formulation of Ny Read More

Background: At present, the main problems of Micro-Electro-Mechanical Systems (MEMS) based temperature detector are the narrow range of temperature detection and difficulty in the measurement of high temperature. Besides, MEMS devices have different response characteristics for various surrounding temperature in the petrochemical and metallurgy application fields with hightemperature and harsh conditions. To e Read More

Background: Glimepiride is a third-generation, oral anti-diabetic sulfonylurea drug, generally recommended for the treatment of type–II diabetes. A biocompatible polymer, Eudragit RS 100 is widely used for the preparation of targeted and time-controlled release of drugs. Glimepiride is encapsulated using Eudragit RS 100 for sustained release delivery. Objective: To develop sustained release microparticles of Glimepiride Read More

Aim: Computation of loss factors for one-bit RF MEMS switch over Ku, K and Ka-band for two different insulating substrates. Objective: Numerical investigation of return loss, insertion loss, isolation loss are computed under both actuated and unactuated states for two different insulating substrates of the 1-bit RF MEMS switch, and corresponding up and down-capacitances are obtained. Methods: The unique characteristic Read More

Aim: Establish the efficient footprint size, i.e., the total substrate width of photonic waveguides (Ridge, Rib, and Slot) under the fundamental mode propagation constraints. Objective: By varying the total substrate width for all photonic waveguides (Ridge, Rib, and Slot) with respect to four major waveguide parameters, namely effective refractive index, propagation loss, propagation length, and confinement percentage, the conv Read More