Skip to content
2000
  1. Home
  2. A-Z Publications
  3. MicroRNA
  4. Fast Track Listing

MicroRNA - Online First

Description text for Online First listing goes here...

1 result

    • The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review

      https://doi.org/10.2174/0122115366304114240904051429
      Available online: 12 September 2024
      Introduction

      Curcumin is known as a bioactive component that is found in the rhizomes of Curcuma longa. Curcumin is well known for its chemo-preventive and anticancer properties. However, its anticancer mechanism in colorectal cancer treatment is unclear, and some studies have shown that many microRNAs (miRs) could be potential targets for curcumin in colorectal cancer (CRC) treatment, so there is a need for their integration and clarification.

      Methods

      We systematically searched international databases, including PubMed, Scopus, and Web of Science, until July 2021 by using some relevant keywords.

      Results

      The search resulted in 87 papers, among which there were 18 related articles. Curcumin was found to cause the upregulation of miR-497, miR-200c, miR-200b, miR-409-3p, miR‐34, miR‐126, miR-145, miR-206, miR-491, miR-141, miR-429, miR-101, and miR-15a and the downregulation of miR-21, miR-155, miR‐221, miR‐222, miR-17-5p, miR-130a, miR-27, and miR-20a.

      Conclusion

      The present review study suggests that curcumin may be useful as a novel therapeutic agent for CRC by altering the expression level of miRs.

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test