Skip to content
2000
Volume 9, Issue 3
  • ISSN: 1573-4064
  • E-ISSN: 1875-6638

Abstract

A series of 2-thioxo-imidazolidin-4-one derivatives were synthesized and were characterized by IR, 1H NMR, 13C NMR, mass spectral data and elemental analysis. All compounds were tested for antifungal and antibacterial activity. Some of the compounds were found to exhibit promising antifungal activity. Molecular modeling investigations showed that the active compounds may interact at the active site of the fungal cytochrome P450- dependent sterol 14α- demethylase in the sterol biosynthesis pathway.

Loading

Article metrics loading...

/content/journals/mc/10.2174/1573406411309030016
2013-05-01
2025-06-07
Loading full text...

Full text loading...

/content/journals/mc/10.2174/1573406411309030016
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test