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- ISSN: 1573-4064
- E-ISSN: 1875-6638
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Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents
- Source: Medicinal Chemistry, Volume 8, Issue 5, Sep 2012, p. 769 - 778
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- 01 Sep 2012
Abstract
A series of 1,3-oxathiolane-based nucleoside analogs 5-methyl substituted was synthesized and tested as potential antiviral agents. Structural characterization and C2-C4 / C2-C5 relative stereochemistry assignments were performed by NMR experiments. All tested isomers were found to be inactive and cytotoxic.
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