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- ISSN: 1573-4064
- E-ISSN: 1875-6638
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BioArena Studies: Unique Function of Endogenous Formaldehyde and Ozone in the Antibiotic Effect - A Review
- Source: Medicinal Chemistry, Volume 8, Issue 1, Jan 2012, p. 75 - 84
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- 01 Jan 2012
Abstract
The investigations demonstrated clearly a unique function and role of endogenous formaldehyde (HCHO) and ozone (O3) in the antibiotic effect of diverse molecules having different chemical structure. Elimination of HCHO and/or O3 from the layer chromatographic spots resulted in a decrease in the antimicrobial activity. On the basis of detection and measure of endogenous HCHO and O3 BioArena enables to both direct isolation and biological evaluation of new bioactive compounds.
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