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- ISSN: 1573-4064
- E-ISSN: 1875-6638
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Labeling Strategies with F-18 for Positron Emission Tomography Imaging
- Source: Medicinal Chemistry, Volume 7, Issue 5, Sep 2011, p. 334 - 344
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- 01 Sep 2011
Abstract
The labeling of probes with fluorine-18 [18F, β(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the fluorine-18 labeling of probes for PET imaging. Problems and issues relating to the practical production of fluorine-18 currently in widespread use are also discussed.
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