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- ISSN: 1573-4064
- E-ISSN: 1875-6638
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Synthesis and DPPH Radical Scavenging Activity of 5-Arylidene-N,Ndimethylbarbiturates
- Source: Medicinal Chemistry, Volume 7, Issue 3, May 2011, p. 231 - 236
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- 01 May 2011
Abstract
Twenty-four derivatives of N,N-dimethylbarbituric acid 1-24 were screened for their DPPH radical scavenging activity. These compounds showed an excellent antioxidant activity. A structure-activity relationship has been discussed, while all the synthetic compounds were characterized by spectroscopic techniques and elemental analysis.
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