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- ISSN: 1573-4064
- E-ISSN: 1875-6638
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Synthesis and Preliminary Biological Evaluation of Chrysin Derivatives as Potential Anticancer Drugs
- Source: Medicinal Chemistry, Volume 6, Issue 1, Jan 2010, p. 6 - 8
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- 01 Jan 2010
Abstract
A series of chrysin derivatives were prepared from 2-hydroxyacetophenone, 2,4-dihydroxyacetophenone, 2,4,6- trihydroxy- acetophenone, using modified Baker-Venkataraman transformation. Their anticancer activities in vitro were evaluated by the standard MTT method. The results of biological test showed that some of chrysin derivatives showed stronger anticancer activity than 5-fluorouracil.
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