Retinoids in Clinical Use

Vincent C. O. Njar; Lalji Gediya; Puranik Purushottamachar; Panka Chopra; Aashvini Belosay; Jyoti B. Patel

doi:10.2174/157340606777724022

ISSN: 1573-4064
E-ISSN: 1875-6638

Retinoids in Clinical Use
Authors: Vincent C. O. Njar¹, Lalji Gediya², Puranik Purushottamachar³, Panka Chopra⁴, Aashvini Belosay⁵ and Jyoti B. Patel⁶
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¹ Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine,Baltimore, MD 2101-1559, USA. ² Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine,Baltimore, MD 2101-1559, USA. ³ Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine,Baltimore, MD 2101-1559, USA. ⁴ Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine,Baltimore, MD 2101-1559, USA. ⁵ Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine,Baltimore, MD 2101-1559, USA. ⁶ Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine,Baltimore, MD 2101-1559, USA.
Source: Medicinal Chemistry, Volume 2, Issue 4, Jul 2006, p. 431 - 438
DOI: https://doi.org/10.2174/157340606777724022
- Available online: 01 Jul 2006

Abstract

Retinoids have been investigated for their therapeutic potential for the past 3 decades. They have a reputation for being both beneficial in the treatment of several diseases and detrimental due to toxic and/or teratogenic side effects. The purpose of this review is to highlight retinoids that are currently used in the clinic. We also discuss their mechanisms of action and research strategies to develop new and safer retinoid-based therapies.

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2006-07-01

2025-05-23

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Article Type: Research Article

Keyword(s): clinical utility; RAR/RXR; retinoic acid metabolism blocking agents (RAMBAs); Retinoids; rexinoids

Retinoids in Clinical Use

Abstract

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