Letters in Organic Chemistry - Volume 12, Issue 8, 2015

This paper describes the synthesis of the novel phosphonato esters from the reaction of dialkyl acetylenedicarboxylates with the N–H acid (4-methylphenyl)sulfonyl hydrazide in the presence of trialkyl(aryl) phosphites at room temperature in excellent yields.

Ru nanoparticles were successfully supported on molecular sieves and it was further characterized by sophisticated analytical methods such as transmission electron microscopy, energy- dispersive X-ray spectroscopy and nitrogen adsorption techniques. Transmission electron microscopy data confirmed, indicated the formation of metal oxide nanoparticles (4.5±2 nm) on the external surface of molecular sieves. Ru suppor Read More

The syntheses of α-D-glucose pentaacetate were studied. Various methods used for the synthesis of α-D-glucose pentaacetate were detailedly discussed.

Silica sulfuric acid (SSA) was used as efficient catalyst for the synthesis of 4Hbenzo[ b]pyran derivatives via the one-pot three-component condensation of aromatic aldehyde (1), 5,5-dimethyl-1,3-cyclohexanedione (2a) or 1,3-cyclohexandione (2b) and malononitrile (3) in aqueous media with high yields. The luminescence of products was studied in detail.

Synthesis of cross-linkable diketopiperadine derivatives is described. Cross-linkable aamino acid methyl esters were subjected to peptide synthesis with Boc-protected glycine or L-tyrosine. No protection of cross-linkable functional groups (catechol and phenylazide) is necessary for the construction of diketopiperazine skeleton.

A new aromaticity index is proposed based on the energy of π orbitals D={[π1+Σn2(π1-πn)]0 /[π1 + Σn2(π1-πn)]} x a, where n are the number of occupied π orbitals and a is the number of cycles in the molecule. Calculations have been performed on aromatic and heteroaromatic compounds by using DFT method at B3LYP/6-311G+(d,p) level. This new index has been tested on a large number of 6π electron compounds, on bic Read More

An efficient and one-pot method for the preparation of 3,4-dihydropyrimidin-2(1H)- ones/thiones is described. Benzyltriphenylphosphonium chloride (BTPPC) under solvent free conditions catalyzes this multi-component condensation reaction to afford the corresponding dihydropyrimidinones/thiones in good yields.

A new D-ring fused steroidal γ-butyrolactone, 3β-hydroxy-5,6-dihydro-17β-methoxypregnan- 21,16α-carbalactone from abundant 20-oxopregnane,5,6-dihydro pregnenolone acetate using the high yield metal mediated C-21 functionalization reaction with MnO2-TMSCl/AcCl-AcOH system as the key step has been described. Furthermore, the application of this reaction paving a way to synthesize 3β,21-diacetoxy -16 Read More

A simple and highly efficient approach for the synthesis of γ-Benzopyranones and 3,4- Dihydropyrimidin-2(1H)-ones/thiones using ammonium acetate as a promoter under thermal as well as microwave irradiation using solvent-free conditions has been demonstrated.

Four organic compounds, N1,N4-bis(6-methylpyridin-2-yl)terephthalamide (1), its di-Noxide (3), mono-N-oxide with water (5w) and di-N-oxide (6) of N1,N3-bis(6-methylpyridin-2-yl) (4) have been synthesized and their solid state structures have also been determined using FTIR, NMR, Mass and single crystal X-ray analysis. Three dimensional propagations, conventional and nonconventional hydrogen bonding with their point of int Read More

A series of novel cationic–non-ionic heterogemini surfactants (Cn-1EC-s-Cm where n and m represents the hydrocarbon chain length of fatty acid and aliphatic amine, n=12, 14, 16, 18, m=12, 14, 16) were synthesized from fatty acid, epichlorohydrin and aldciphatic amine. The chemicals tructures of the surfactants were characterized by IR spectra, NMR, ESI-MS and elemental analysis. Their critical micelle concentrations Read More

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