Full text loading...
- ISSN: 1570-1786
- E-ISSN:
-
Synthesis and Characterization of Some New Spirothiadiazole Oxindoles and their Mannich Bases
- Source: Letters in Organic Chemistry, Volume 19, Issue 12, Dec 2022, p. 1136 - 1140
-
- 01 Dec 2022
Abstract
A series of new spirothiadiazole oxindoles were synthesized by the reaction of 4-amino-5- mercapto-3-[(1H-indol-3-yl)methyl]-1,2,4-triazole and isatin derivatives. The reaction of spiro [indole] thiadiazoles with formaldehyde and piperidine afforded the corresponding Mannich bases. The structures of newly synthesized compounds were characterized by IR, 1D-NMR, 2D-NMR, and LC/MS spectral data.
© Bentham Science Publishers