Chemoenzymatic Approach to a (R)-3, 4-Diaminobutanoic Acid Derivative with a Suitable Orthogonal Protection for Solid Phase Peptide Synthesis

Monica Lopez-Garcia; Ignacio Alfonso; Vicente Gotor

doi:10.2174/1570178043401054

ISSN: 1570-1786
E-ISSN: 1875-6255

Chemoenzymatic Approach to a (R)-3, 4-Diaminobutanoic Acid Derivative with a Suitable Orthogonal Protection for Solid Phase Peptide Synthesis
Authors: Monica Lopez-Garcia¹, Ignacio Alfonso² and Vicente Gotor³
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¹ Departamento de Quimica Organica e Inorganica, Facultad de Quimica, Universidad de Oviedo, Julian Clavería, 8, 33006 Oviedo, Spain ² Departamento de Quimica Organica e Inorganica, Facultad de Quimica, Universidad de Oviedo, Julian Clavería, 8, 33006 Oviedo, Spain ³ Departamento de Quimica Organica e Inorganica, Facultad de Quimica, Universidad de Oviedo, Julian Clavería, 8, 33006 Oviedo, Spain
Source: Letters in Organic Chemistry, Volume 1, Issue 3, Jul 2004, p. 254 - 256
DOI: https://doi.org/10.2174/1570178043401054
- Available online: 01 Jul 2004

Abstract

The efficient chemoenzymatic synthesis of a (R)-3,4-diaminobutanoic acid derivative has been achieved. The final compound has suitable orthogonal protection for solid phase peptide synthesis.

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2004-07-01

2025-06-23

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Article Type: Review Article

Keyword(s): amino acids; enzymes; orthogonal protection; peptide synthesis

Chemoenzymatic Approach to a (R)-3, 4-Diaminobutanoic Acid Derivative with a Suitable Orthogonal Protection for Solid Phase Peptide Synthesis

Abstract

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