Re-Evaluation of a Solid-Phase Hydantoin Synthesis

Jesus Vazquez; Miriam Royo; Fernando Albericio

doi:10.2174/1570178043400992

ISSN: 1570-1786
E-ISSN: 1875-6255

Re-Evaluation of a Solid-Phase Hydantoin Synthesis
Authors: Jesus Vazquez¹, Miriam Royo² and Fernando Albericio³
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¹ Barcelona Biomedical Research Institute, Barcelona Science Park, University of Barcelona, 08028-Barcelona, Spain ² Barcelona Biomedical Research Institute, Barcelona Science Park, University of Barcelona, 08028-Barcelona, Spain ³ Barcelona Biomedical Research Institute, Barcelona Science Park, University of Barcelona, 08028-Barcelona, Spain
Source: Letters in Organic Chemistry, Volume 1, Issue 3, Jul 2004, p. 224 - 226
DOI: https://doi.org/10.2174/1570178043400992
- Available online: 01 Jul 2004

Abstract

Solid-phase methods for the preparation of hydantoins are reviewed. Furthermore, an optimized method based on the concourse of 1,1'-carbonyldiimidazole allows the preparation of hydantoins without loss of chiral integrity.

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2004-07-01

2025-05-07

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Article Type: Review Article

Keyword(s): amino acid; combinatorial chemistry; cyclization; libraries; solid support

Re-Evaluation of a Solid-Phase Hydantoin Synthesis

Abstract

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