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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Synthesis, Nematicidal Activity and Docking Study of Novel Pyrazole-4-Carboxamide Derivatives Against Meloidogyne incognita
- Source: Letters in Drug Design & Discovery, Volume 16, Issue 1, Jan 2019, p. 29 - 35
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- 01 Jan 2019
Abstract
Background: A series of novel 2,6-dichloro-4-(trifluoromethyl)phenyl)-3-(difluoromethyl)- 1H-pyrazole-4-carboxamide derivatives were designed and synthesized. Methods: All the title compounds were confirmed by 1H NMR and MS. Results and Conclusion: The primarily nematicidal activity results indicated that some of them exhibited moderate control efficacy against the tomato root-knot nematode disease caused by Meloidogyne incognita.
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