A Brief Overview on Chemistry and Biology of Benzoxepine

Background: The present review article is related to the synthesis and medicinal importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the branch of organic / medicinal chemistry and always attracts the attention of chemists working not only in the area of organic synthesis but also in natural products. Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative, antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of this class of compounds. Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.