Nematicidal Activity of Sprio and Bridged Heterocyclic Neonicotinoid Analogues against Meloidogyne incognita

Neonicotinoids are the most widely used insecticides currently, but their nematicidal activity was seldom reported. A series of spiro or bridged heterocyclic neonicotinoid analoges was prepared and their nematicidal activity was evaluated. Most of the synthesized compounds showed moderate to good nematicidal activity against Meloidogyne incognita. The investigations here provide the novel nematicidal chemotypes which can be used as leads for further structured modifications.