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2000
Volume 8, Issue 6
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

2,4-Disubstituted pyrroles were polycondensed and tested for lipid-lowering effects in mice. Fluoro-substituted pyrrole monomers and polymers lowered total serum cholesterol by 30-35% and LDL-cholesterol by 47-64%. The lipidlowering effects were similar for polymers and their monomers, however, the polymers produced these effects at dosage concentrations 1/8th that of the monomers.

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/content/journals/lddd/10.2174/157018011795906839
2011-07-01
2025-08-18
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