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Making Drops in Microencapsulation Processes
- Source: Letters in Drug Design & Discovery, Volume 7, Issue 4, May 2010, p. 300 - 309
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- 01 May 2010
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Abstract
The present work is a review of classical and recently developed methods for drop production in micro- and nanoencapsulation processes. Most of the methods and technologies used in microencapsulation processes require the formation of drops as a previous step. The drop formation step is very influential for the subsequent microparticle size and size distribution. These parameters, together with the microparticle structure, usually determine the application. The most important methods and technologies used to generate drops are briefly described. These have been divided into three large groups as a function of their production rate and capacity for drop-size control. A comparative review is completed, reporting the main advantages and disadvantages of the key technologies.