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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Inhibition of 17β -Hydroxysteroid Dehydrogenase (17β -HSD) by Imidazole-Based Compounds
- Source: Letters in Drug Design & Discovery, Volume 5, Issue 1, Jan 2008, p. 48 - 51
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- 01 Jan 2008
Abstract
We report the results of the biochemical evaluation of a series of imidazole-based compounds against the hydroxysteroid dehydrogenase (HSD) family of enzymes, in particular, types 1 and 3 of 17β-HSD and 3β-HSD. The results show that the synthesised compounds were good inhibitors of this family of enzymes.
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