Full text loading...
- ISSN: 1570-1808
- E-ISSN: 1875-628X
-
Synthesis and Biological Evaluation of a New Series of Benzothiazole-Benzothiadiazine Conjugates as Antibacterial Agents
- Source: Letters in Drug Design & Discovery, Volume 4, Issue 8, Dec 2007, p. 550 - 556
-
- 01 Dec 2007
Abstract
A new series of benzothiazolo-benzothiadiazine hybrids (9a-g) has been synthesized and evaluated for their antibacterial activity against clinical isolates of Gram-positive and Gram-negative bacteria. Some of these hybrids in this series exhibited antibacterial activity comparable to ampicillin. In addition, some of the compounds showed DNA gyrase inhibitory activity at a moderate level compared to ciprofloxacin.
© Bentham Science Publishers