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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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In Vitro Cytotoxicity Evaluation of Some Substituted Indazole Derivatives
- Source: Letters in Drug Design & Discovery, Volume 4, Issue 7, Oct 2007, p. 467 - 470
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- 01 Oct 2007
Abstract
A new series of 1- and 6-Substituted 1H-indazoles 2-6 were synthesized in moderate yield, through a simple synthetic strategy using 6-nitroindazole as key intermediate. The cytotoxicity of synthetic compounds was evaluated against kidney carcinoma cell line (BSR) and the human larynx carcinoma (Hep). Some of the newly prepared compounds indicated significant inhibitory activity against these cells in vitro.
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