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2000
Volume 4, Issue 7
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

We report the preliminary results into the synthesis and evaluation of triazole-based compounds against the components of 17α-hydroxylase/17,20-lyase (P45017α), namely 17α-hydroxylase (17α-OHase) and 17,20-lyase (lyase). The results show that the compounds are weaker than ketoconazole but are good lead compounds in the search for inhibitors of P45017α, in particular, lyase.

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/content/journals/lddd/10.2174/157018007781788471
2007-10-01
2025-06-01
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/content/journals/lddd/10.2174/157018007781788471
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  • Article Type:
    Research Article
Keyword(s): 17,20-lyase; 17α-hydroxylase; Evaluation; P45017α; Synthesis; Triazole
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