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2000
Volume 4, Issue 3
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

We report the search for non-steroidal inhibitors of 17β-hydroxysteroid dehydrogenase, in particular, for types 1 and 3. The results show that the synthesised compounds based on the biphenyl backbone were good inhibitors of 17β-HSD1, but were weak inhibitors of 17β-HSD3. The compounds were evaluated against 3β-HSD but showed weak inhibition.

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/content/journals/lddd/10.2174/157018007780077417
2007-04-01
2025-06-11
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