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2000
Volume 4, Issue 2
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

Phosphodiesterases are clinical targets for congestive heart failure, erectile dysfunction and inflammation. Intake of carotenoids decreases the risk of cardiovascular and inflammatory diseases. Therefore, phosphodiesterase binding of the carotenoid derivative disodium disuccinate astaxanthin (Cardax) was investigated using molecular modeling methods. Cardax was predicted to bind to PDE5A at the catalytic site.

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/content/journals/lddd/10.2174/157018007779422497
2007-03-01
2025-05-28
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/content/journals/lddd/10.2174/157018007779422497
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