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2000
Volume 4, Issue 1
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

New ultrasound contrast agents that incorporate a therapeutic compound have become of interest. Such an ultrasound contrast agent particle might act as the vehicle to carry a drug or gene load to a perfused region of interest. The load could be released with the assistance of ultrasound. Generally, an increase in shell thickness increases the acoustic amplitude needed to disrupt a bubble. High acoustic amplitudes, however, have been associated with unwanted effects on cells. It would be interesting to incorporate a droplet containing drugs or genes inside a microbubble carrier. A liquid core surrounded by a gas encapsulation has been referred to as antibubble. In this paper, the creation of an antibubble with the aid of ultrasound has been demonstrated with high-speed photography.

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/content/journals/lddd/10.2174/157018007778992847
2007-01-01
2025-05-28
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/content/journals/lddd/10.2174/157018007778992847
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  • Article Type:
    Research Article
Keyword(s): Antibubble; Drug delivery; High-speed photography; Ultrasound contrast agent
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