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2000
Volume 2, Issue 8
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

Five polydentate ligands 2-6 were prepared from arylamines and precursors 1a-b. The polydentate (2-4) and (5) showed marked activity against cancer cell lines. The substituents (R and R') appear to play a key role in the cytotoxic potency of this class of compounds.

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/content/journals/lddd/10.2174/157018005774717299
2005-12-01
2025-05-28
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/content/journals/lddd/10.2174/157018005774717299
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  • Article Type:
    Review Article
Keyword(s): cancer; cytotoxicity; Polydentate N-ligands; pyrazole
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