Design of a New Phosphate Binder, Anion Exchange Resin, Based on Microcalorimeter Measurements

Hiroyoshi Inoue; Sho-ichi Yamagishi

doi:10.2174/1570180053765138

ISSN: 1570-1808
E-ISSN: 1875-628X

Design of a New Phosphate Binder, Anion Exchange Resin, Based on Microcalorimeter Measurements
Authors: Hiroyoshi Inoue¹ and Sho-ichi Yamagishi²
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¹ Radioisotope Institute for Basic and Clinical Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan. ² Radioisotope Institute for Basic and Clinical Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Source: Letters in Drug Design & Discovery, Volume 2, Issue 3, May 2005, p. 250 - 254
DOI: https://doi.org/10.2174/1570180053765138
- Available online: 01 May 2005

Abstract

It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.

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2005-05-01

2025-05-25

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Article Type: Review Article

Keyword(s): ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium; gastrointestinal content; immersion heat; phosphate binding; sevelamer hci; wetting

Design of a New Phosphate Binder, Anion Exchange Resin, Based on Microcalorimeter Measurements

Abstract

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