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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Synthesis and Characterization of a Novel Protein Tyrosine Phosphatase Inhibitor, 2-(Cyclobutylamino)- N- (2-Furylmethyl)-2-Thioxoacetamide
- Source: Letters in Drug Design & Discovery, Volume 2, Issue 3, May 2005, p. 224 - 227
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- 01 May 2005
Abstract
The synthesis and biological activities of a series of 2-amino-2-thioxoacetamide derivatives are described. These compounds have inhibitory effects against the protein tyrosine phosphatase activity of CD45. Compound 4i inhibited the PCA reaction in vivo.
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