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2000
Volume 21, Issue 15
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

Background

Alkaloids are important phytoconstituents obtained from various plant sources.

Methods

The main objective of the study was to evaluate the anti-infective potential of alkaloids against 14α-demethylase, transpeptidase, and omicron spike protein using molecular docking studies. The potential constituents were identified and an ADMET study was performed.

Results

The study concluded that reserpine and tubocurarine exhibited potential activity against the three tested enzymes with good ADMET profile.

Conclusion

Reserpine and tubocurarine can further be explored to attain new candidates as anti-infective agents.

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2024-01-24
2024-12-30
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  • Article Type:
    Rapid Communication
Keyword(s): 14α-demethylase; ADMET study; alkaloids; molecular docking; omicron; transpeptidase
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