Acute Cystitis Caused by Commensal Neisseria oralis: A Case Report and Review of the Literature

Background: Neisseria are usually harmless inhabitants of otherwise asymptomatic persons’ upper respiratory mucosal surfaces. Method: It is, therefore, expected that a disturbance in the physiology leads to nongonococcal, non-meningococcal Neisseria becoming pathogenic. Result: We report the case of a diabetic man who initially presented with nonspecific symptoms and was later found to have cystitis caused by N. oralis. Conclusion: We also review the pertinent literature and discuss available evidence on pathophysiological mechanisms of infection with such commensal bacteria.