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Volume 25, Issue 3
  • ISSN: 1871-5265
  • E-ISSN: 2212-3989

Abstract

Objective

The current study aimed to formulate and evaluate herbal gels containing essential oils for the treatment of infection caused by microbial species, ., and These species are also responsible for acne directly and indirectly.

Material and Methods

The gels were prepared using a gelling agent with 1% Carbopol940, and they were further evaluated for physical appearance, drug content, drug release, viscosity, extrudability, pH, and spreadability. Further, anti-microbial screening was done with various microbial species.

Results

Studies revealed that the gel was highly effective against the selected species except for the fungal strain. ZOI was observed ranging from 3.1 ± 0.01 mm to 13.4 ± 0.14 mm. The maximum ZOI was observed at 13.4 ± 0.14 mm against The physical properties of the gel satisfied the standard parameters.

Conclusion

The prepared herbal gel was found to have highly promising activity against bacterial species associated with bacterial infection but in a dose-dependent manner. However, more research is required.

© 2025 Bentham Science Publishers
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2024-09-12
2025-03-30

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/content/journals/iddt/10.2174/0118715265293665240905043446
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Formulation and Comparison of Herbal Gels Containing Essential Oils and their Antimicrobial Evaluation
Infect. Disord. Drug Targets 25, E18715265293665 (2025); https://doi.org/10.2174/0118715265293665240905043446
/content/journals/iddt/10.2174/0118715265293665240905043446
/content/journals/iddt/10.2174/0118715265293665240905043446
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  • Article Type:     Research Article
Keyword(s): drug content; Essential oils; gel; pH; S. aureus; skin infection

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