Nature as Source and Inspiration for the Synthesis of New Anticancer Drugs

Daniele Passarella; Alessandra Giardini; Giordano Lesma; Alessandra Silvani; Bruno Danieli

doi:10.2174/1574089054583641

ISSN: 1574-0897
E-ISSN:

Nature as Source and Inspiration for the Synthesis of New Anticancer Drugs
Authors: Daniele Passarella¹, Alessandra Giardini², Giordano Lesma³, Alessandra Silvani⁴ and Bruno Danieli⁵
View Affiliations Hide Affiliations

Affiliations: ¹ Dipartimento di Chimica Organica e Industriale, Universita degli Studi di Milano, Via Venezian, 21 - 20133 Milano, Italy. ² Dipartimento di Chimica Organica e Industriale, Universita degli Studi di Milano, Via Venezian, 21 - 20133 Milano, Italy. ³ Dipartimento di Chimica Organica e Industriale, Universita degli Studi di Milano, Via Venezian, 21 - 20133 Milano, Italy. ⁴ Dipartimento di Chimica Organica e Industriale, Universita degli Studi di Milano, Via Venezian, 21 - 20133 Milano, Italy. ⁵ Dipartimento di Chimica Organica e Industriale, Universita degli Studi di Milano, Via Venezian, 21 - 20133 Milano, Italy.
Source: Frontiers in Natural Product Chemistry, Volume 1, Issue 1, Jan 2005, p. 51 - 54
DOI: https://doi.org/10.2174/1574089054583641
- Available online: 01 Jan 2005

Abstract

The bifunctional taxoid-colchicinoid hybrids were synthesised and evaluated in assays of cytotoxicity and tubulin assembly/disassembly. All compounds showed a high degree of cytotoxicity.

Article metrics loading...

/content/journals/fnpc/10.2174/1574089054583641

2005-01-01

2024-11-23

From This Site

/content/journals/fnpc/10.2174/1574089054583641

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/fnpc/10.2174/1574089054583641

Article Type: Review Article

Keyword(s): alkaloids; anticancer agents; biological activity; cannabinoids; furanocoumarins; multi-drug resistance

Nature as Source and Inspiration for the Synthesis of New Anticancer Drugs

Abstract

From This Site

Most Read This Month