Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders)
  4. Volume 25, Issue 4
  5. Article
Volume 25, Issue 4
  • ISSN: 1871-5303
  • E-ISSN: 2212-3873
file format pdf download PDF
file format text download EPUB
side by side viewer icon HTML

Abstract

Introduction

Premature Ovarian Insufficiency (POI) is the most common reproductive aging disorder in women of reproductive age, which is characterized by decreased ovarian function in women before the age of 40. Etiology research of POI has garnered interest and attention from scholars worldwide over the past decades.

Methods

However, to the best of our knowledge, no comprehensive survey with bibliometric analysis has been conducted yet on the research trends of POI etiology. This article aimed to analyze current scientific findings on the etiology of POI, offering innovative ideas for further research. Research articles on the etiology of POI from 1994 to 2023 were collected from the Web of Science Core Collection. A total of 456 research articles were included, and the total number of publications increased annually. We used VOSviewer and bibliometric.com to analyze the keywords, terms, institution, publication country/region, author name, publication journal, and the sum of times the articles have been cited.

Results

This study has shown that a research hotspot is the genetic etiology of POI; however, there is still a lack of research on the impact of epigenetic alterations, iatrogenic injuries, environmental pollution, social stress, and unhealthy lifestyles on the pathogenesis of POI.

Conclusion

The factors illustrated here represent potential future directions for POI etiology research and warrant more attention from researchers.

© 2025 Bentham Science Publishers
© 2025 The Author(s). Published by Bentham Science Publisher. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
Loading

Article metrics loading...

/content/journals/emiddt/10.2174/0118715303313887240624071238
2024-06-25
2025-05-21

  • From This Site

    /content/journals/emiddt/10.2174/0118715303313887240624071238
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
The full text of this item is not currently available.

References

  1. LiM. ZhuY. WeiJ. ChenL. ChenS. LaiD. The global prevalence of premature ovarian insufficiency: A systematic review and meta-analysis.Climacteric20232629510210.1080/13697137.2022.2153033 36519275
     [Google Scholar]
  2. JutiviboonsukA. SalangL. EamudomkarnN. MahakkanukrauhA. SuwannarojS. FoocharoenC. Prevalence and clinical associations with premature ovarian insufficiency, early menopause, and low ovarian reserve in systemic sclerosis.Clin. Rheumatol.20214062267227510.1007/s10067‑020‑05522‑5 33244723
     [Google Scholar]
  3. GolezarS. RamezaniT.F. KhazaeiS. EbadiA. KeshavarzZ. The global prevalence of primary ovarian insufficiency and early menopause: A meta-analysis.Climacteric201922440341110.1080/13697137.2019.1574738 30829083
     [Google Scholar]
  4. MukaT. Oliver-WilliamsC. KunutsorS. LavenJ.S.E. FauserB.C.J.M. ChowdhuryR. KavousiM. FrancoO.H. Association of age at onset of menopause and time since onset of menopause with cardiovascular outcomes, intermediate vascular traits, and all-cause mortality.JAMA Cardiol.20161776777610.1001/jamacardio.2016.2415 27627190
     [Google Scholar]
  5. De VosM. DevroeyP. FauserB.C.J.M. Primary ovarian insufficiency.Lancet2010376974491192110.1016/S0140‑6736(10)60355‑8 20708256
     [Google Scholar]
  6. WebberL. DaviesM. AndersonR. BartlettJ. BraatD. CartwrightB. CifkovaR. de Muinck Keizer-SchramaS. HogervorstE. JanseF. LiaoL. VlaisavljevicV. ZillikensC. VermeulenN. ESHRE Guideline: Management of women with premature ovarian insufficiency.Hum. Reprod.201631592693710.1093/humrep/dew027 27008889
     [Google Scholar]
  7. Thaung ZawJ.J. HoweP.R.C. WongR.H.X. Postmenopausal health interventions: Time to move on from the Women’s Health Initiative?Ageing Res. Rev.201848798610.1016/j.arr.2018.10.005 30355506
     [Google Scholar]
  8. FarquharC.M. BhattacharyaS. ReppingS. MastenbroekS. KamathM.S. MarjoribanksJ. BoivinJ. Female subfertility.Nat. Rev. Dis. Primers201951710.1038/s41572‑018‑0058‑8 30679436
     [Google Scholar]
  9. ZhuZ. XuW. LiuL. Ovarian aging: Mechanisms and intervention strategies.Med Rev20232659061010.1515/mr‑2022‑0031 37724254
     [Google Scholar]
  10. KeH. TangS. GuoT. HouD. JiaoX. LiS. LuoW. XuB. ZhaoS. LiG. ZhangX. XuS. WangL. WuY. WangJ. ZhangF. QinY. JinL. ChenZ.J. Landscape of pathogenic mutations in premature ovarian insufficiency.Nat. Med.202329248349210.1038/s41591‑022‑02194‑3 36732629
     [Google Scholar]
  11. QinY. JiaoX. SimpsonJ.L. ChenZ.J. Genetics of primary ovarian insufficiency: New developments and opportunities.Hum. Reprod. Update201521678780810.1093/humupd/dmv036 26243799
     [Google Scholar]
  12. TurkyilmazA. AlavandaC. AtesE.A. GeckinliB.B. PolatH. GokcuM. KarakayaT. CebiA.H. SoylemezM.A. GuneyA.İ. AtaP. ArmanA. Whole-exome sequencing reveals new potential genes and variants in patients with premature ovarian insufficiency.J. Assist. Reprod. Genet.202239369571010.1007/s10815‑022‑02408‑0 35066699
     [Google Scholar]
  13. PankiewiczK. LaudańskiP. IssatT. The role of noncoding RNA in the pathophysiology and treatment of premature ovarian insufficiency.Int. J. Mol. Sci.20212217933610.3390/ijms22179336 34502244
     [Google Scholar]
  14. ChengJ. HuangJ. YuanS. ZhouS. YanW. ShenW. ChenY. XiaX. LuoA. ZhuD. WangS. Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes.PLoS One2017126e017788810.1371/journal.pone.0177888 28644873
     [Google Scholar]
  15. GuoY. SunJ. LaiD. Role of microRNAs in premature ovarian insufficiency.Reprod. Biol. Endocrinol.20171513810.1186/s12958‑017‑0256‑3 28499456
     [Google Scholar]
  16. SzeligaA. Calik-KsepkaA. Maciejewska-JeskeM. GrymowiczM. SmolarczykK. KostrzakA. SmolarczykR. RudnickaE. MeczekalskiB. Autoimmune diseases in patients with premature ovarian insufficiency—our current state of knowledge.Int. J. Mol. Sci.2021225259410.3390/ijms22052594 33807517
     [Google Scholar]
  17. KirshenbaumM. OrvietoR. Premature ovarian insufficiency (POI) and autoimmunity-an update appraisal.J. Assist. Reprod. Genet.201936112207221510.1007/s10815‑019‑01572‑0 31440958
     [Google Scholar]
  18. SharifK. WatadA. BridgewoodC. KanducD. AmitalH. ShoenfeldY. Insights into the autoimmune aspect of premature ovarian insufficiency.Best Pract. Res. Clin. Endocrinol. Metab.201933610132310.1016/j.beem.2019.101323 31606343
     [Google Scholar]
  19. JiaoX. ZhangX. LiN. ZhangD. ZhaoS. DangY. ZanvitP. JinW. ChenZ.J. ChenW. QinY. T reg deficiency‐mediated T H 1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells.Clin. Transl. Med.2021116e44810.1002/ctm2.448 34185428
     [Google Scholar]
  20. TuckerE.J. GroverS.R. BachelotA. TouraineP. SinclairA.H. Premature ovarian insufficiency: New perspectives on genetic cause and phenotypic spectrum.Endocr. Rev.201637660963510.1210/er.2016‑1047 27690531
     [Google Scholar]
  21. CuiW. RocconiR.P. ThotaR. AndersonR.A. BruinoogeS.S. ComstockI.A. DenduluriN. GassmanA. GralowJ. HuttK.J. Amiri-KordestaniL. LambertiniM. LeightonJ. LuK.H. Mostoufi-MoabS. PollastroT. PradhanS. SaberH. SchenkelC. SprattD. WedamS. PhillipsK.A. Measuring ovarian toxicity in clinical trials: An american society of clinical oncology research statement.Lancet Oncol.20232410e415e42310.1016/S1470‑2045(23)00390‑X 37797647
     [Google Scholar]
  22. McGlacken-ByrneS.M. ConwayG.S. Premature ovarian insufficiency.Best Pract. Res. Clin. Obstet. Gynaecol.2022819811010.1016/j.bpobgyn.2021.09.011 34924261
     [Google Scholar]
  23. ChonS.J. UmairZ. YoonM.S. Premature ovarian insufficiency: Past, present, and future.Front. Cell Dev. Biol.2021967289010.3389/fcell.2021.672890 34041247
     [Google Scholar]
  24. ShellingA.N. Ahmed NasefN. The role of lifestyle and dietary factors in the development of premature ovarian insufficiency.Antioxidants2023128160110.3390/antiox12081601 37627595
     [Google Scholar]
  25. Hashemi SheikhshabaniS. Ghafouri-FardS. HosseiniE. OmraniM.D. A novel homozygote nonsense variant of MSH4 leads to primary ovarian insufficiency and non-obstructive azoospermia.Mol. Biol. Rep.20245116810.1007/s11033‑023‑09000‑4 38175272
     [Google Scholar]
  26. YangX. RenS. YangJ. PanY. ZhouZ. ChenQ. FangY. ShangL. ZhangF. ZhangX. WuY. Rare variants in FANCJ induce premature ovarian insufficiency in humans and mice.J. Genet. Genomics202451225225510.1016/j.jgg.2023.03.013 37062450
     [Google Scholar]
  27. ZhaoD. LiJ. SeehusC. HuangX. ZhaoM. ZhangS. WangW. JiH.L. GuoF. Bibliometric analysis of recent sodium channel research.Channels201812131132510.1080/19336950.2018.1511513 30134757
     [Google Scholar]
  28. JabaleyC.S. GroffR.F.IV StentzM.J. MollV. LyndeG.C. BlumJ.M. O’Reilly-ShahV.N. Highly visible sepsis publications from 2012 to 2017: Analysis and comparison of altmetrics and bibliometrics.J. Crit. Care20184835737110.1016/j.jcrc.2018.09.033 30296750
     [Google Scholar]
  29. LiZ. QiuL.X. WuF.X. YangL.Q. SunY.M. LuZ.J. YuW.F. Assessing the national productivity in subspecialty critical care medicine journals: A bibliometric analysis.J. Crit. Care2012276747.e1747.e510.1016/j.jcrc.2012.03.002 23217574
     [Google Scholar]
  30. CaiH. ShaS. ZhangQ. SiT.L. LiuY.F. ZhengW.Y. SuZ. CheungT. UngvariG.S. TeoA.R. KatoT.A. NgC.H. XiangY.T. Hikikomori: A perspective from bibliometric analysis.Psychiatry Clin. Neurosci.2023771054154910.1111/pcn.13573 37350640
     [Google Scholar]
  31. GuC. WangZ. PanY. ZhuS. GuZ. Tungsten‐based nanomaterials in the biomedical field: A bibliometric analysis of research progress and prospects.Adv. Mater.2023351220439710.1002/adma.202204397 35906814
     [Google Scholar]
  32. JiangS. LiuY. ZhengH. ZhangL. ZhaoH. SangX. XuY. LuX. Evolutionary patterns and research frontiers in neoadjuvant immunotherapy: A bibliometric analysis.Int. J. Surg.202310992774278310.1097/JS9.0000000000000492 37216225
     [Google Scholar]
  33. MuirD.C.G. GetzingerG.J. McBrideM. FergusonP.L. How many chemicals in commerce have been analyzed in environmental media? A 50 year bibliometric analysis.Environ. Sci. Technol.202357259119912910.1021/acs.est.2c09353 37319372
     [Google Scholar]
  34. MaC. SuH. LiH. Global research trends on prostate diseases and erectile dysfunction: A bibliometric and visualized study.Front. Oncol.20211062789110.3389/fonc.2020.627891 33643922
     [Google Scholar]
  35. YeungA.W.K. TzvetkovN.T. BalachevaA.A. GeorgievaM.G. GanR.Y. JozwikA. PyzelB. HorbańczukJ.O. NovellinoE. DurazzoA. LucariniM. CamilliE. SoutoE.B. AtanasovA.G. SantiniA. Lignans: Quantitative analysis of the research literature.Front. Pharmacol.2020113710.3389/fphar.2020.00037 32116713
     [Google Scholar]
  36. ZhangY. LiA.A. XiaoS.N. ZhongN.S. TongW.L. WangS.J. LiuJ.M. LiuZ.L. A bibliometric analysis of publications on spinal cord injury treatment with glucocorticoids using vosviewer.Front. Public Health20221090737210.3389/fpubh.2022.907372 36003626
     [Google Scholar]
  37. ZhaoM. ZhangH. LiZ. A bibliometric and visual analysis of nanocomposite hydrogels based on VOSviewer from 2010 to 2022.Front. Bioeng. Biotechnol.20221091425310.3389/fbioe.2022.914253 35814005
     [Google Scholar]
  38. ZhouR. LinX. LiuD. LiZ. ZengJ. LinX. LiangX. Research hotspots and trends analysis of TFEB: A bibliometric and scientometric analysis.Front. Mol. Neurosci.20221585495410.3389/fnmol.2022.854954 35531069
     [Google Scholar]
  39. ZyoudS.H. Al-JabiS.W. AmerR. ShakhshirM. ShahwanM. JairounA.A. AkkawiM. Abu TahaA. Global research trends on the links between the gut microbiome and cancer: A visualization analysis.J. Transl. Med.20222018310.1186/s12967‑022‑03293‑y 35148757
     [Google Scholar]
  40. YangK. HuY. QiH. Digital health literacy: Bibliometric analysis.J. Med. Internet Res.2022247e3581610.2196/35816 35793141
     [Google Scholar]
  41. ZhangJ. SongL. JiaJ. TianW. LaiR. ZhangZ. LiJ. JuJ. XuH. Knowledge mapping of necroptosis from 2012 to 2021: A bibliometric analysis.Front. Immunol.20221391715510.3389/fimmu.2022.917155 35769473
     [Google Scholar]
  42. ZhangX. LuY. WuS. ZhaoX. LiS. ZhangS. TanJ. Estimates of global research productivity in primary ovarian insufficiency from 2000 to 2021: Bibliometric analysis.Front. Endocrinol.20221395990510.3389/fendo.2022.959905 36387882
     [Google Scholar]
  43. SmithD.R. Bibliometrics, dermatology and contact dermatitis.Contact Dermat.200859313313610.1111/j.1600‑0536.2008.01405.x 18759892
     [Google Scholar]
  44. JinY. LiX. YuanQ. HuangX. ZhangD. Visualization analysis of exercise intervention on Alzheimer disease based on bibliometrics: Trends, hotspots and topics.Medicine202310249e3634710.1097/MD.0000000000036347 38065914
     [Google Scholar]
  45. ShiJ. BendigD. VollmarH.C. RascheP. Mapping the bibliometrics landscape of ai in medicine: Methodological study.J. Med. Internet Res.202325e4581510.2196/45815 38064255
     [Google Scholar]
  46. LiuZ. ZhouC. GuoH. WangM. LiangJ. ZhangY. Knowledge mapping of global status and trends for thromboangiitis obliterans: A bibliometrics and visual analysis.J. Pain Res.2023164071408710.2147/JPR.S437521 38054111
     [Google Scholar]
  47. ZhangJ. Bibliometrics and visualization analysis of literature on male hypogonadism from 2000 to 2023: Research focus and frontiers.Int. J. Impot. Res.2023364312323 38052978
     [Google Scholar]
  48. HeZ. DaiL. ZuoY. ChenY. WangH. ZengH. Hotspots and frontiers in pulmonary arterial hypertension research: A bibliometric and visualization analysis from 2011 to 2020.Bioengineered2022136146671468010.1080/21655979.2022.2100064 35880647
     [Google Scholar]
  49. ZhaoY. PeiF. YangN. SunH. GaoZ. TianQ. LuX. Epidemiological and clinical characteristics of human ocular helaziasis in China from 2011 to 2022 based on bibliometrics.Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi2023355513516 38148542
     [Google Scholar]
  50. ZhengY. LiJ. LiuB. XieZ. HeY. XueD. ZhaoD. HaoC. Global trends in PANoptosis research: Bibliometrics and knowledge graph analysis.Apoptosis2024291-222924210.1007/s10495‑023‑01889‑3 37751105
     [Google Scholar]
  51. ZhouY. GuJ. YuH. ChenF. LongC. MaihemutiM. ChenT. ZhangW. Screening and identification of esr1 as a target of icaritin in hepatocellular carcinoma: Evidence from bibliometrics and bioinformatic analysis.Curr. Mol. Pharmacol.2023 38239068
     [Google Scholar]
  52. ZhouZ. LongH. ZhouL. XuX. ZhangR. TuN. LiuF. XiongJ. Visual analysis of autoimmune dry eye studies based on bibliometrics.Medicine202310247e3602810.1097/MD.0000000000036028 38013305
     [Google Scholar]
  53. JiaoX. KeH. QinY. ChenZ.J. Molecular genetics of premature ovarian insufficiency.Trends Endocrinol. Metab.2018291179580710.1016/j.tem.2018.07.002 30078697
     [Google Scholar]
  54. Rivero-MüllerA. HuhtaniemiI. Genetic variants of gonadotrophins and their receptors: Impact on the diagnosis and management of the infertile patient.Best Pract. Res. Clin. Endocrinol. Metab.202236110159610.1016/j.beem.2021.101596 34802912
     [Google Scholar]
  55. ChenY. LinM. ZhuangD. Wastewater treatment and emerging contaminants: Bibliometric analysis.Chemosphere202229713393210.1016/j.chemosphere.2022.133932 35149018
     [Google Scholar]
  56. LiS. DingH. YangY. YuB. ChenM. Global research status of pathological scar reported over the period 2001–2021: A 20‐YEAR bibliometric analysis.Int. Wound J.20232051725173810.1111/iwj.13988 36274191
     [Google Scholar]
  57. HuangQ. ChenS. ChenJ. ShiQ. LinS. Therapeutic options for premature ovarian insufficiency: An updated review.Reprod. Biol. Endocrinol.20222012810.1186/s12958‑022‑00892‑8 35120535
     [Google Scholar]
  58. PellicerN. CozzolinoM. Diaz-GarcíaC. GallianoD. CoboA. PellicerA. HerraizS. Ovarian rescue in women with premature ovarian insufficiency: Facts and fiction.Reprod. Biomed. Online202346354356510.1016/j.rbmo.2022.12.011 36710157
     [Google Scholar]
  59. EvangelinakisN. GeladariE.V. GeladariC.V. KontogeorgiA. PapaioannouG.K. PeppaM. KalantaridouS. The influence of environmental factors on premature ovarian insufficiency and ovarian aging.Maturitas202417910787110.1016/j.maturitas.2023.107871 37925867
     [Google Scholar]
  60. QiaoJ. WangY. LiX. JiangF. ZhangY. MaJ. SongY. MaJ. FuW. PangR. ZhuZ. ZhangJ. QianX. WangL. WuJ. ChangH.M. LeungP.C.K. MaoM. MaD. GuoY. QiuJ. LiuL. WangH. NormanR.J. LawnJ. BlackR.E. RonsmansC. PattonG. ZhuJ. SongL. HeskethT. A lancet commission on 70 years of women’s reproductive, maternal, newborn, child, and adolescent health in China.Lancet2021397102932497253610.1016/S0140‑6736(20)32708‑2 34043953
     [Google Scholar]
  61. CoulamC.B. AdamsonS.C. AnnegersJ.F. Incidence of premature ovarian failure.Obstet. Gynecol.1986674604606 3960433
     [Google Scholar]
  62. LuborskyJ.L. MeyerP. SowersM.F. GoldE.B. SantoroN. Premature menopause in a multi-ethnic population study of the menopause transition.Hum. Reprod.200318119920610.1093/humrep/deg005 12525467
     [Google Scholar]
  63. ChemaitillyW. LiZ. KrasinM.J. BrookeR.J. WilsonC.L. GreenD.M. KloskyJ.L. BarnesN. ClarkK.L. FarrJ.B. Fernandez-PinedaI. BishopM.W. MetzgerM. PuiC.H. KasteS.C. NessK.K. SrivastavaD.K. RobisonL.L. HudsonM.M. YasuiY. SklarC.A. Premature ovarian insufficiency in childhood cancer survivors: A report from the St. J.Clin. Endocrinol. Metab.201710272242225010.1210/jc.2016‑3723 28368472
     [Google Scholar]
  64. AndanyN. KaidaA. de PokomandyA. YudinM.H. WangL. KennedyV.L. WebsterK. LoutfyM. Prevalence and correlates of early-onset menopause among women living with HIV in Canada.Menopause2020271667510.1097/GME.0000000000001423 31688411
     [Google Scholar]
  65. NetterlidA. MörseH. GiwercmanA. HenicE. ÅkessonK.E. ErfurthE.M. ElfvingM. Premature ovarian failure after childhood cancer and risk of metabolic syndrome: A cross-sectional analysis.Eur. J. Endocrinol.20211851677510.1530/EJE‑20‑1275 33914702
     [Google Scholar]
  66. LimY.M. JeongK. LeeS.R. ChungH.W. LeeW. Association between premature ovarian insufficiency, early menopause, socioeconomic status in a nationally representative sample from Korea.Maturitas2019121222710.1016/j.maturitas.2018.12.004 30704561
     [Google Scholar]
  67. WuX. CaiH. KallianpurA. LiH. YangG. GaoJ. XiangY.B. JiB.T. Yu-Tang; Zheng, W.; Shu, X.O. Impact of premature ovarian failure on mortality and morbidity among Chinese women.PLoS One201493e8959710.1371/journal.pone.0089597 24603759
     [Google Scholar]
  68. Rostami DovomM. Bidhendi-YarandiR. MohammadK. FarahmandM. AziziF. Ramezani TehraniF. Prevalence of premature ovarian insufficiency and its determinants in Iranian populations: Tehran lipid and glucose study.BMC Womens Health20212117910.1186/s12905‑021‑01228‑1 33622308
     [Google Scholar]
  69. MolitorisJ. KantorováV. EzdiS. GonnellaG. Early childbearing and child marriage: An update.Stud. Fam. Plann.202354350352110.1111/sifp.12243 37408105
     [Google Scholar]
  70. OrazulikeN.C. JeremiahI. GreenK.I. UzoigweS.A. Effect of age on childbearing in port harcourt, Nigeria.Int. J. Biomed. Sci.2015112828510.59566/IJBS.2015.11082 26199581
     [Google Scholar]
  71. AhinkorahB.O. Maternal age at first childbirth and under-five morbidity in sub-Saharan Africa: Analysis of cross-sectional data of 32 countries.Arch. Public Health202179115110.1186/s13690‑021‑00674‑5 34425906
     [Google Scholar]
  72. Arkhangel’skiiV. KalachikovaO.g. Maternal age at first birth: Dynamics, regional differences, determination.Econ. Soc. Changes: Facts Trends Forecast202013520021710.15838/esc.2020.5.71.12
     [Google Scholar]
  73. SinghS. DarrochJ.E. Adolescent pregnancy and childbearing: Levels and trends in developed countries.Fam. Plann. Perspect.2000321142310.2307/2648144 10710702
     [Google Scholar]
  74. DuganE. BlachS. BiondiM. CaiZ. DePaolaM. EstesC. FeldJ. GamkrelidzeI. KottililS. MaS. MathurP. MontoyaS. Razavi-ShearerD. Razavi-ShearerK. Robbins-ScottS. SchmelzerJ. RazaviH. Global prevalence of hepatitis C virus in women of childbearing age in 2019: A modelling study.Lancet Gastroenterol. Hepatol.20216316918410.1016/S2468‑1253(20)30359‑9 33515496
     [Google Scholar]
  75. ShinJ. HanK. JungJ.H. ParkH.J. KimW. HuhY. KimY.H. KimD.H. KimS.M. ChoiY.S. ChoK.H. NamG.E. Age at menopause and risk of heart failure and atrial fibrillation: A nationwide cohort study.Eur. Heart J.202243404148415710.1093/eurheartj/ehac364 36239217
     [Google Scholar]
  76. VerrilliL.E. Allen-BradyK. JohnstoneE.B. AlvordM.A. WeltC.K. Family size for women with primary ovarian insufficiency and their relatives.Hum. Reprod.202338101991199710.1093/humrep/dead168 37632248
     [Google Scholar]
  77. MurrayC.J.L. CallenderC.S.K.H. KulikoffX.R. SrinivasanV. AbateD. AbateK.H. AbayS.M. AbbasiN. AbbastabarH. AbdelaJ. AbdelalimA. Abdel-RahmanO. AbdiA. AbdoliN. AbdollahpourI. AbdulkaderR.S. AbebeH.T. AbebeM. AbebeZ. AbeboT.A. AbejieA.N. AboyansV. AbrahaH.N. AbreuD.M.X. AbrhamA.R. Abu-RaddadL.J. Abu-RmeilehN.M.E. AccrombessiM.M.K. AcharyaP. AdamuA.A. AdebayoO.M. AdedejiI.A. AdekanmbiV. AdetokunbohO.O. AdhenaB.M. AdhikariT.B. AdibM.G. AdouA.K. AdsuarJ.C. AfaridehM. AfshinA. AgarwalG. AgesaK.M. AghayanS.A. AgrawalS. AhmadiA. AhmadiM. AhmedM.B. AhmedS. AichourA.N. AichourI. AichourM.T.E. AkandaA.S. AkbariM.E. AkibuM. AkinyemiR.O. AkinyemijuT. AkseerN. AlahdabF. Al-AlyZ. AlamK. AlebelA. AlemanA.V. AleneK.A. Al-EyadhyA. AliR. AlijanzadehM. Alizadeh-NavaeiR. AljunidS.M. AlkerwiA. AllaF. AllebeckP. AlmasiA. AlonsoJ. Al-RaddadiR.M. AlsharifU. AltirkawiK. Alvis-GuzmanN. AmareA.T. AmmarW. AnberN.H. AndreiC.L. AndroudiS. AnimutM.D. AnsariH. AnshaM.G. AntonioC.A.T. AppiahS.C.Y. AremuO. AreriH.A. ArianN. ÄrnlövJ. ArtamanA. AryalK.K. AsayeshH. AsfawE.T. AsgedomS.W. AssadiR. AteyT.M.M. AtiqueS. AtterayaM.S. AusloosM. AvokpahoE.F.G.A. AwasthiA. Ayala QuintanillaB.P. AyeleY. AyerR. AyukT.B. AzzopardiP.S. BabalolaT.K. BabazadehA. BadaliH. BadawiA. BaliA.G. BanachM. Barker-ColloS.L. BärnighausenT.W. BarreroL.H. BasaleemH. BassatQ. BasuA. BauneB.T. BaynesH.W. BeghiE. BehzadifarM. BehzadifarM. BekeleB.B. BelachewA.B. BelayA.G. BelayE. BelayS.A. BelayY.A. BellM.L. BelloA.K. BennettD.A. BensenorI.M. BergeronG. BerhaneA. BermanA.E. BernabeE. BernsteinR.S. BertolacciG.J. BeuranM. BhattaraiS. BhaumikS. BhuttaZ.A. BiadgoB. BijaniA. BikbovB. BililignN. Bin SayeedM.S. BirlikS.M. BirungiC. BiswasT. BizunehH. BleyerA. BasaraB.B. BosettiC. BoufousS. BradyO.J. BragazziN.L. BraininM. BrazinovaA. BreitbordeN.J.K. BrennerH. BrewerJ.D. BriantP.S. BrittonG. BursteinR. BusseR. ButtZ.A. Cahuana-HurtadoL. Campos-NonatoI.R. Campuzano RinconJ.C. CanoJ. CarM. CárdenasR. CarreroJ.J. CarvalhoF. Castañeda-OrjuelaC.A. Castillo RivasJ. CastroF. Catalá-LópezF. ÇavlinA. CerinE. ChalekJ. ChangH-Y. ChangJ-C. ChattopadhyayA. ChaturvediP. ChiangP.P-C. ChinK.L. ChisumpaV.H. ChitheerA. ChoiJ-Y.J. ChowdhuryR. ChristopherD.J. CicuttiniF.M. CiobanuL.G. CirilloM. ClaroR.M. Collado-MateoD. ComfortH. ConstantinM-M. ContiS. CooperC. CooperL.T. CornabyL. CortesiP.A. CortinovisM. CostaM. CromwellE. CroweC.S. CukeljP. CunninghamM. DabaA.K. DachewB.A. DandonaL. DandonaR. DarganP.I. DaryaniA. Das GuptaR. Das NevesJ. DasaT.T. DashA.P. WeaverN.D. DavitoiuD.V. DavletovK. De LeoD. De NeveJ-W. DegefaM.G. DegenhardtL. DegfieT.T. DeiparineS. DemozG.T. DemtsuB. Denova-GutiérrezE. DeribeK. DervenisN. Des JarlaisD.C. DessieG.A. DharmaratneS.D. DhimalM. DickerD. DingE.L. DinsaG.D. DjalaliniaS. DoH.P. DokovaK. DokuD.T. DolanK.A. DoyleK.E. DriscollT.R. DubeyM. DubljaninE. DukenE.E. DuraesA.R. EbrahimpourS. EdvardssonD. El BcheraouiC. El-KhatibZ. ElyazarI.R. EnayatiA. EndriesA.Y. ErmakovS.P. EshratiB. EskandariehS. EsmaeiliR. EsteghamatiA. EsteghamatiS. EstepK. FakhimH. FaragT. FaramarziM. FareedM. FarinhaC.S.E.S. FaroA. FarvidM.S. FarzadfarF. FarzaeiM.H. FayK.A. FazeliM.S. FeiginV.L. FeiglA.B. FeizyF. FennyA.P. FentahunN. FereshtehnejadS-M. FernandesE. FeyissaG.T. FilipI. FinegoldS. FischerF. FlorL.S. FoigtN.A. ForemanK.J. FornariC. FürstT. FukumotoT. FullerJ.E. FullmanN. GakidouE. GallusS. GamkrelidzeA. GanjiM. GankpeF.G. GarciaG.M. Garcia-GordilloM.Á. GebreA.K. GebreT. GebregergsG.B. GebrehiwotT.T. GebremedhinA.T. GelanoT.F. GelawY.A. GeleijnseJ.M. Genova-MalerasR. GethingP. GezaeK.E. GhadamiM.R. GhadimiR. GhadiriK. Ghasemi FalavarjaniK. Ghasemi-KasmanM. GhiasvandH. GhimireM. GhoshalA.G. GillP.S. GillT.K. GiussaniG. GnedovskayaE.V. GoliS. GomezR.S. Gómez-DantésH. GonaP.N. GoodridgeA. GopalaniS.V. GoulartA.C. GoulartB.N.G. GradaA. GrossoG. GugnaniH.C.C. GuoJ. GuoY. GuptaP.C. GuptaR. GuptaR. GuptaT. HaagsmaJ.A. HachinskiV. Hafezi-NejadN. HagosT.B. HailegiyorgisT.T. HailuG.B. Haj-MirzaianA. Haj-MirzaianA. HamadehR.R. HamidiS. HandalA.J. HankeyG.J. HaoY. HarbH.L. HaririanH. HaroJ.M. HasanM. HassankhaniH. HassenH.Y. HavmoellerR. HayS.I. HeY. Hedayatizadeh-OmranA. HegazyM.I. HeibatiB. HeidariB. HendrieD. HenokA. HenryN.J. HerteliuC. HeydarpourF. HibstuD.T. HoleM.K. Homaie RadE. HoogarP. HosgoodH.D. HosseiniS.M. Hosseini ChavoshiM.M. HosseinzadehM. HostiucM. HostiucS. HsairiM. HsiaoT. HuG. HuangJ.J. IburgK.M. IgumborE.U. IkedaC.T. IlesanmiO.S. IqbalU. IrensoA.A. IrvaniS.S.N. IsehunwaO.O. IslamS.M.S. JahangiryL. JahanmehrN. JainS.K. JakovljevicM. JaluM.T. JamesS.L. JassalS.K. JavanbakhtM. JayatillekeA.U. JeemonP. JhaR.P. JhaV. JiJ.S. JonasJ.B. JozwiakJ.J. JungariS.B. JürissonM. KabirZ. KadelR. KahsayA. KalaniR. KapilU. KaramiM. MatinB.K. KarchA. KaremaC. KarimiS.M. KasaeianA. KassaD.H. KassaG.M. KassaT.D. KassaZ.Y. KassebaumN.J. KastorA. KatikireddiS.V. KaulA. KawakamiN. KaryaniA.K. KebedeS. KeiyoroP.N. KempG.R. KengneA.P. KerenA. KereselidzeM. KhaderY.S. KhafaieM.A. KhajaviA. KhalidN. KhalilI.A. KhanE.A. KhanM.S. KhangY-H. KhannaT. KhaterM.M. KhatonyA. KhazaeipourZ. KhazaieH. KhojaA.T. KhosraviA. KhosraviM.H. KibretG.D. KidanemariamZ.T. KiirithioD.N. KilgoreP.E. KimD. KimJ.Y. KimY-E. KimY.J. KimokotiR.W. KinfuY. KinraS. KisaA. KivimäkiM. KochharS. KokuboY. KololaT. KopecJ.A. KosekM.N. KosenS. KoulP.A. KoyanagiA. KrishanK. KrishnaswamiS. KrohnK.J. DefoB.K. BicerB.K. KumarG.A. KumarM. KumarP. KumsaF.A. KutzM.J. LadS.D. LafranconiA. LalD.K. LallooR. LamH. LamiF.H. LangJ.J. LanksyS. LansinghV.C. LaryeaD.O. LassiZ.S. LatifiA. LaxmaiahA. LazarusJ.V. LeeJ.B. LeeP.H. LeighJ. LeshargieC.T. LetaS. LeviM. LiS. LiX. LiY. LiangJ. LiangX. LibenM.L. LimL-L. LimenihM.A. LinnS. LiuS. LorkowskiS. LotufoP.A. LozanoR. LuneviciusR. MabikaC.M. MacarayanE.R.K. MackayM.T. MadottoF. MahmoodT.A.E. MahotraN.B. MajdanM. MajdzadehR. MajeedA. MalekzadehR. MalikM.A. MamunA.A. ManamoW.A. MandaA-L. MangalamS. MansourniaM.A. MantovaniL.G. MapomaC.C. MaramiD. MaravillaJ.C. MarcenesW. MarinaS. Martins-MeloF.R. MärzW. MarzanM.B. Mashamba-ThompsonT.P. MasiyeF. Mason-JonesA.J. MassenburgB.B. MathurM.R. MaulikP.K. MazidiM. McGrathJ.J. MehataS. MehendaleS.M. MehndirattaM.M. MehrotraR. MehrzadiS. MehtaK.M. MehtaV. MekonnenT.C. MelesH.G. MelesK.G. MeleseA. MelkuM. MemiahP.T.N. MemishZ.A. MendozaW. MengeshaM.M. MengistuD.T. MengistuG. MensahG.A. MeretaS.T. MeretojaA. MeretojaT.J. MestrovicT. MezgebeH.B. MiangotarY. MiazgowskiB. MiazgowskiT. MillerT.R. Miller-PetrieM.K. MiniG.K. MirabiP. MiricaA. MirrakhimovE.M. MisganawA.T. MoazenB. MohammadK.A. MohammadiM. MohammadifardN. Mohammadi-KhanaposhtaniM. MohammedM.A. MohammedS. MokdadA.H. MolaG.D. MolokhiaM. MonastaL. MontañezJ.C. MoradiG. MoradiM. Moradi-LakehM. MoradinazarM. MoragaP. Morgado-Da-CostaJ. MoriR. MorrisonS.D. MosapourA. MoschosM.M. MousaviS.M. MucheA.A. MuchieK.F. MuellerU.O. MukhopadhyayS. MullerK. MurphyT.B. MurthyG.V.S. MusaJ. MusaK.I. MustafaG. MuthupandianS. NachegaJ.B. NagelG. NaghaviM. NaheedA. NahvijouA. NaikG. NaikP. NajafiF. NaldiL. NangiaV. NansseuJ.R. NascimentoB.R. NawazH. NcamaB.P. NeamatiN. NegoiI. NegoiR.I. NeupaneS. NewtonC.R.J. NgalesoniF.N. NgunjiriJ.W. NguyenG. NguyenL.H. NguyenT.H. NingrumD.N.A. NirayoY.L. NisarM.I. NixonM.R. NomuraS. NorooziM. NoubiapJ.J. NouriH.R. ShiadehM.N. NowrooziM.R. NyandwiA. NyasuluP.S. OdellC.M. Ofori-AsensoR. OgahO.S. OgboF.A. OhI-H. OkoroA. OladimejiO. OlagunjuA.T. OlagunjuT.O. OlivaresP.R. OlusanyaB.O. OlusanyaJ.O. OngS.K. OrtizA. Osgood-ZimmermanA. OtaE. OtienoB.A. OtstavnovS.S. OwolabiM.O. OyekaleA.S. P A, M.; Pakhale, S.; Pakhare, A.P.; Pana, A.; Panda, B.K.; Panda-Jonas, S.; Pandey, A.R.; Park, E-K.; Parsian, H.; Patel, S.; Patil, S.T.; Patle, A.; Patton, G.C.; Paturi, V.R.; Paudel, D.; Pedroso, M.M.; Peprah, E.K.; Pereira, D.M.; Perico, N.; Pesudovs, K.; Petri, W.A.; Petzold, M.; Pierce, M.; Pigott, D.M.; Pillay, J.D.; Pirsaheb, M.; Polanczyk, G.V.; Postma, M.J.; Pourmalek, F.; Pourshams, A.; Poustchi, H.; Prakash, S.; Prasad, N.; Purcell, C.A.; Purwar, M.B.; Qorbani, M.; Quansah, R.; Radfar, A.; Rafay, A.; Rafiei, A.; Rahim, F.; Rahimi-Movaghar, A.; Rahimi-Movaghar, V.; Rahman, M.; Rahman, M.S.; Rahman, M.H.U.; Rahman, M.A.; Rahman, S.U.; Rai, R.K.; Rajati, F.; Rajsic, S.; Ram, U.; Ranabhat, C.L.; Ranjan, P.; Rawaf, D.L.; Rawaf, S.; Ray, S.E.; Razo-García, C.; Reiner, R.C.; Reis, C.; Remuzzi, G.; Renzaho, A.M.N.; Resnikoff, S.; Rezaei, S.; Rezaeian, S.; Rezai, M.S.; Riahi, S.M.; Rios-Blancas, M.J.; Roba, K.T.; Roberts, N.L.S.; Roever, L.; Ronfani, L.; Roshandel, G.; Rostami, A.; Rubagotti, E.; Ruhago, G.M.; Sabde, Y.D.; Sachdev, P.S.; Saddik, B.; Saeedi Moghaddam, S.; Safari, H.; Safari, Y.; Safari-Faramani, R.; Safdarian, M.; Safi, S.; Safiri, S.; Sagar, R.; Sahebkar, A.; Sahraian, M.A.; Sajadi, H.S.; Salahshoor, M.R.; Salam, N.; Salama, J.S.; Salamati, P.; Saldanha, R.D.F.; Saleem, Z.; Salimi, Y.; Salimzadeh, H.; Salomon, J.A.; Salvi, S.S.; Salz, I.; Sambala, E.Z.; Samy, A.M.; Sanabria, J.; Sanchez-Niño, M.D.; Santos, I.S.; Santric Milicevic, M.M.; Sao Jose, B.P.; Sardana, M.; Sarker, A.R.; Sarmiento-Suárez, R.; Saroshe, S.; Sarrafzadegan, N.; Sartorius, B.; Sarvi, S.; Sathian, B.; Satpathy, M.; Sawant, A.R.; Sawhney, M.; Saxena, S.; Schaeffner, E.; Schelonka, K.; Schneider, I.J.C.; Schwebel, D.C.; Schwendicke, F.; Seedat, S.; Sekerija, M.; Sepanlou, S.G.; Serván-Mori, E.; Shabaninejad, H.; Shackelford, K.A.; Shafieesabet, A.; Shaheen, A.A.; Shaikh, M.A.; Shakir, R.A.; Shams-Beyranvand, M.; Shamsi, M.; Shamsizadeh, M.; Sharafi, H.; Sharafi, K.; Sharif, M.; Sharif-Alhoseini, M.; Sharma, J.; Sharma, R.; She, J.; Sheikh, A.; Shi, P.; Shibuya, K.; Shigematsu, M.; Shiri, R.; Shirkoohi, R.; Shiue, I.; Shokraneh, F.; Shukla, S.R.; Si, S.; Siabani, S.; Sibai, A.M.; Siddiqi, T.J.; Sigfusdottir, I.D.; Sigurvinsdottir, R.; Silpakit, N.; Silva, D.A.S.; Silva, J.P.; Silveira, D.G.A.; Singam, N.S.V.; Singh, J.A.; Singh, N.P.; Singh, V.; Sinha, D.N.; Sliwa, K.; Soares Filho, A.M.; Sobaih, B.H.; Sobhani, S.; Soofi, M.; Soriano, J.B.; Soyiri, I.N.; Sreeramareddy, C.T.; Starodubov, V.I.; Steiner, C.; Stewart, L.G.; Stokes, M.A.; Strong, M.; Subart, M.L.; Sufiyan, M.B.; Sulo, G.; Sunguya, B.F.; Sur, P.J.; Sutradhar, I.; Sykes, B.L.; Sylaja, P.N.; Sylte, D.O.; Szoeke, C.E.I.; Tabarés-Seisdedos, R.; Tabb, K.M.; Tadakamadla, S.K.; Tandon, N.; Tassew, A.A.; Tassew, S.G.; Taveira, N.; Tawye, N.Y.; Tehrani-Banihashemi, A.; Tekalign, T.G.; Tekle, M.G.; Temsah, M-H.; Terkawi, A.S.; Teshale, M.Y.; Tessema, B.; Teweldemedhin, M.; Thakur, J.S.; Thankappan, K.R.; Thirunavukkarasu, S.; Thomas, N.; Thomson, A.J.; Tilahun, B.; To, Q.G.; Tonelli, M.; Topor-Madry, R.; Torre, A.E.; Tortajada-Girbés, M.; Tovani-Palone, M.R.; Toyoshima, H.; Tran, B.X.; Tran, K.B.; Tripathy, S.P.; Truelsen, T.C.; Truong, N.T.; Tsadik, A.G.; Tsegay, A.; Tsilimparis, N.; Tudor Car, L.; Ukwaja, K.N.; Ullah, I.; Usman, M.S.; Uthman, O.A.; Uzun, S.B.; Vaduganathan, M.; Vaezi, A.; Vaidya, G.; Valdez, P.R.; Varavikova, E.; Varughese, S.; Vasankari, T.J.; Vasconcelos, A.M.N.; Venketasubramanian, N.; Villafaina, S.; Violante, F.S.; Vladimirov, S.K.; Vlassov, V.; Vollset, S.E.; Vos, T.; Vosoughi, K.; Vujcic, I.S.; Wagnew, F.S.; Waheed, Y.; Walson, J.L.; Wang, Y.; Wang, Y-P.; Weiderpass, E.; Weintraub, R.G.; Weldegwergs, K.G.; Werdecker, A.; Westerman, R.; Whiteford, H.; Widecka, J.; Widecka, K.; Wijeratne, T.; Winkler, A.S.; Wiysonge, C.S.; Wolfe, C.D.A.; Wu, S.; Wyper, G.M.A.; Xu, G.; Yamada, T.; Yano, Y.; Yaseri, M.; Yasin, Y.J.; Ye, P.; Yentür, G.K.; Yeshaneh, A.; Yimer, E.M.; Yip, P.; Yisma, E.; Yonemoto, N.; Yoon, S-J.; Yotebieng, M.; Younis, M.Z.; Yousefifard, M.; Yu, C.; Zadnik, V.; Zaidi, Z.; Zaman, S.B.; Zamani, M.; Zare, Z.; Zeleke, M.M.; Zenebe, Z.M.; Zerfu, T.A.; Zhang, X.; Zhao, X-J.; Zhou, M.; Zhu, J.; Zimsen, S.R.M.; Zodpey, S.; Zoeckler, L.; Lopez, A.D.; Lim, S.S. Population and fertility by age and sex for 195 countries and territories, 1950–2017: A systematic analysis for the global burden of disease study 2017.Lancet2018392101591995205110.1016/S0140‑6736(18)32278‑5 30496106
     [Google Scholar]
  78. ZhouZ. ZhengD. WuH. LiR. XuS. KangY. CaoY. ChenX. ZhuY. XuS. ChenZ-J. MolB.W. QiaoJ. Epidemiology of infertility in China: A population‐based study.BJOG2018125443244110.1111/1471‑0528.14966 29030908
     [Google Scholar]
  79. TongY. ChengN. JiangX. WangK. WangF. LinX. WangF. The trends and hotspots in premature ovarian insufficiency therapy from 2000 to 2022.Int. J. Environ. Res. Public Health202219181172810.3390/ijerph191811728 36142002
     [Google Scholar]
  80. ShiS. LvJ. ChaiR. XueW. XuX. ZhangB. LiY. WuH. SongQ. HuY. Opportunities and challenges in cardio-oncology: A bibliometric analysis from 2010 to 2022.Curr. Probl. Cardiol.202348810122710.1016/j.cpcardiol.2022.101227 35500730
     [Google Scholar]
  81. LinJ. LingF. HuangP. ChenM. SongM. LuK. WangW. The development of GABAergic network in depression in recent 17 years: A visual analysis based on citespace and vosviewer.Front. Psychiatry20221387413710.3389/fpsyt.2022.874137 35664493
     [Google Scholar]
  82. FranićD. FranićD. IvovićM. Tančić-GajićM. MarinaL. BaracM. VujovićS. Genetic etiology of primary premature ovarian insufficiency.Acta Clin. Croat.201655462963510.20471/acc.2016.55.04.14 29117655
     [Google Scholar]
  83. Schuh-HuertaS.M. JohnsonN.A. RosenM.P. SternfeldB. CedarsM.I. Reijo PeraR.A. Genetic markers of ovarian follicle number and menopause in women of multiple ethnicities.Hum. Genet.2012131111709172410.1007/s00439‑012‑1184‑0 22696150
     [Google Scholar]
  84. MorrisD.H. JonesM.E. SchoemakerM.J. AshworthA. SwerdlowA.J. Familial concordance for age at natural menopause.Menopause201118995696110.1097/gme.0b013e31820ed6d2 21505370
     [Google Scholar]
  85. SilvénH. SavukoskiS.M. PesonenP. PukkalaE. GisslerM. SuvantoE. NiinimäkiM. Incidence and familial risk of premature ovarian insufficiency in the Finnish female population.Hum. Reprod.20223751030103610.1093/humrep/deac014 35134918
     [Google Scholar]
  86. FrançaM.M. MendoncaB.B. Genetics of ovarian insufficiency and defects of folliculogenesis.Best Pract. Res. Clin. Endocrinol. Metab.202236110159410.1016/j.beem.2021.101594 34794894
     [Google Scholar]
  87. Garrido-TorresN. Ruiz-VeguillaM. Olivé MasJ. Rodríguez GangosoA. Canal-RiveroM. Juncal-RuizM. Gómez-RevueltaM. Ayesa-ArriolaR. Crespo-FacorroB. Vázquez-BourgonJ. Metabolic syndrome and related factors in a large sample of antipsychotic naïve patients with first-episode psychosis: 3 years follow-up results from the PAFIP cohort.Spanish J Psy Mental Health202316317518310.1016/j.rpsm.2022.05.003 38520081
     [Google Scholar]
  88. LiJ. HanM. ChenY. WuB. WuY. JiaW. LiuJ. LuoH. YuP. TuJ. KuangJ. YiY. Prediction of recurrent ischaemic stroke using radiomics data and machine learning methods in patients with acute ischaemic stroke: Protocol for a multicentre, large sample, prospective observational cohort study in China.BMJ Open20231310e07640610.1136/bmjopen‑2023‑076406 37816554
     [Google Scholar]
  89. FangC. SunX. FanF. ZhangX. WangO. ZhengH. PengZ. LuoX. ChenA. ZhangW. DrmanacR. PetersB.A. SongZ. KristiansenK. High-resolution single-molecule long-fragment rRNA gene amplicon sequencing of bacterial and eukaryotic microbial communities.Cell Reports Methods20233310043710.1016/j.crmeth.2023.100437 37056375
     [Google Scholar]
  90. McElwainM.A. PetersB.A. Accurate sequencing and haplotyping from 10 cells using long fragment read (LFR) technology.Methods Mol. Biol.20232590718410.1007/978‑1‑0716‑2819‑5_5 36335493
     [Google Scholar]
  91. WangG. ZhouZ. JinW. ZhangX. ZhangH. WangX. Single-cell transcriptome sequencing reveals spatial distribution of IL34+ cancer-associated fibroblasts in hepatocellular carcinoma tumor microenvironment.NPJ Precis. Oncol.20237113310.1038/s41698‑023‑00483‑9 38081923
     [Google Scholar]
  92. RazzoukS. Single‐cell sequencing, spatial transcriptome ad periodontitis: Rethink pathogenesis and classification.Oral Dis.2023odi.1476110.1111/odi.14761 37794757
     [Google Scholar]
  93. LiR. WangZ. WangJ.W. LiL. Combining single-cell RNA sequencing with spatial transcriptome analysis reveals dynamic molecular maps of cambium differentiation in the primary and secondary growth of trees.Plant Commun.20234510066510.1016/j.xplc.2023.100665 37491818
     [Google Scholar]
  94. ZhaoX. ShiW. LiuX. ZhangW. Emerging trends and research priorities in premature ovarian insufficiency genes: A bibliometric and visualization study.Gynecol. Endocrinol.2023391228303310.1080/09513590.2023.2283033 38010136
     [Google Scholar]
  95. La MarcaA. BrozzettiA. SighinolfiG. MarzottiS. VolpeA. FalorniA. Primary ovarian insufficiency: Autoimmune causes.Curr. Opin. Obstet. Gynecol.201022427728210.1097/GCO.0b013e32833b6c70 20543691
     [Google Scholar]
/content/journals/emiddt/10.2174/0118715303313887240624071238
Loading
A Glimpse of Research Trends and Frontiers in the Etiology of Premature Ovarian Insufficiency via Bibliometric Analysis
Endocr Metab Immune Disord Drug Targets 25, 310 (2025); https://doi.org/10.2174/0118715303313887240624071238
/content/journals/emiddt/10.2174/0118715303313887240624071238
/content/journals/emiddt/10.2174/0118715303313887240624071238
Loading

Data & Media loading...


  • Article Type:     Review Article
Keyword(s): bibliometric analysis; etiology; etiology research; pathogenesis; Premature ovarian insufficiency; VOSviewer

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test