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- Volume 15, Issue 3, 2022
Drug Metabolism and Bioanalysis Letters - Volume 15, Issue 3, 2022
Volume 15, Issue 3, 2022
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Role of the Gut Microbiome in Diabetes and Cardiovascular Diseases Including Restoration and Targeting Approaches- A Review
Authors: Alka Ahuja, Saraswathy MP, Nandakumar S, Arul P. F, Gurpreet KN and Dhanalekshmi UMMetabolic diseases, including cardiovascular diseases (CVD) and diabetes, have become the leading cause of morbidity and mortality worldwide. Gut microbiota appears to play a vital role in human disease and health, according to recent scientific reports. The gut microbiota plays an important role in sustaining host physiology and homeostasis by creating a cross-talk between the host and microbiome via metabolites Read More
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Biological Importance and Therapeutic Benefit of Rhamnocitrin: A Review of Pharmacology and Analytical Aspects
More LessBackground: Humans have a long history of the uses of plant based products, including extracts and pure phytoconstituents for the treatment of human diseases in the different system of medicine. In the developing countries, phytoproducts play an important role in the healthcare systems due to their medicinal importance and pharmacological activities. Flavonoids class phytochemicals are beneficial for human beings beca Read More
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The Unethical Use of Paracetamol As a Food Tenderizer in Four Selected African Countries: A Major Public Health Concern?
Paracetamol poisoning is the commonest cause of acute liver injury. Therefore, the unethical use of paracetamol as a food tenderizer poses a threat to human health. Although this is a common practice in Ghana, Uganda, Nigeria, and Kenya, there are few or no scientific records on the use of paracetamol as a food tenderizer and its deleterious effects, thus making it difficult to regulate this practice. This review aims to fully Read More
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The Potential Therapeutic Properties of Prunetin against Human Health Complications: A Review of Medicinal Importance and Pharmacological Activities
Authors: Kanika Patel and Dinesh K. PatelBackground: Flavonoids are polyphenolic compounds found to be present in nature and abundant in flowers and fruits. Flavonoidal class phytochemicals have gained interest in the scientific field because of their important pharmacological activities. Several scientific studies have revealed anti-bacterial, anti-oxidant, anti-fungal, analgesic, anti-viral, anti-inflammatory, anti-tumor, anti-parasitic and anti-allergic activi Read More
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In Vitro Inhibitory Effects of Agarwood Tea (Aquilaria malaccensis Lamk) Aqueous Extract on Human Cytochrome P450 (CYP) Enzyme Activities
Authors: Pan Yan, Ung Y. Tze, Premika A/P R Jagadish, Lim Kuan Hon, Lamia N. S. Chowdhury, Shang Tao and Ong Chin EngBackground: Agarwood tea derived from Aquilaria malaccensis Lamk is becoming an increasingly popular herbal drink that is said to have multiple health benefits. Co-administration of this tea and clinical used drugs is possible, but it increases the risk of drug-herb interactions. Objective: This in vitro study investigated the inhibitory effects of agarwood tea aqueous extract on the eight major human drug-metabolising cytochrome Read More
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Berberine Recovered Oxidative Stress Induced by Sodium Nitrite in Rat Erythrocytes
More LessObjective: Berberine, a plant derived alkaloid, present in Berberis species is well known as one of the most important antioxidants. The current research aimed to study the heamatoprotective characteristics of berberine and clarify its plausible mechanisms against sodium nitrite. Methods: Forty numbers of male Sprague Dawley rats were categorized into five equal groups, including group 1: control (normal saline); group 2: Read More
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