Current Spectroscopy and Chromatography - Current Issue
Volume 10, Issue 1, 2024
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Method Development and Validation of Stability-Indicating HPLC-UV Method for Determination of 5 -Fluorouracil
Authors: Diksha Gulati, Deepshi Arora, Yugam Taneja and Ashwani DhingraIntroductionIn the realm of pharmaceutical analysis, the development and validation of a High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV) method for the precise determination of 5-FU stand as a crucial endeavor.MethodsThis study outlines the systematic process of method development, optimization, and subsequent validation to ensure the reliability and applicability of the method in pharmaceuti Read More
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Book Review: Applications of Ion Exchange Materials in Biomedical Industries
The book titled “Applications of Ion Exchange Materials in Biomedical Industries,” edited by Inamuddin, was published by Springer in 2019. The book has 235 pages, and the print version has ISBN 978-3-030-06081-7. The eBook version has ISBN 978-3-030-06082-4 and is available at https://doi.org/10.1007/978-3-030-06082-4. Ion exchange chromatography has become increasingly popular in recent years due to its us Read More
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Optimization of a Validated Liquid Chromatographic Method with Chemometric Approach for Estimation of Eugenol from Seed Powder Extract and Perform Anti-oxidant Activity
BackgroundDeveloped and validated a new reverse phase high-performance liquid chromatographic (RP-HPLC) method, and it is prompt, precise, sensitive and robust for the estimation of eugenol in seed powder extract of Myristica fragrans.ObjectiveThe chemometric approach was utilized to obtain a rugged and definitive chromatographic method for the purpose.MethodsMethod variables such as acetonitrile (%) and flow rate Read More
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- Analytical Chemistry
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A Statistical-based Stability-Indicating Assay for the Estimation of Salbutamol and Ketotifen using HPLC and HPTLC Methods
BackgroundThere are very few methods for simultaneously determining a combined dose of SAL and KET.ObjectivesThe current study aims to explore accurate, precise, simple, and cost-effective HPLC and HPTLC techniques for the simultaneous assessment of Salbutamol (SAL) and Ketotifen (KET).MethodsThe determination of Salbutamol and Ketotifen was performed by HPLC and HPTLC methods using 280 nm Read More
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Standardization and Evaluation of Triphala Juice and Quantification of Gallic Acid as a Biomarker by Analytical Techniques
Authors: Tejas Ahire, Seema Gosavi, Sarita Pawar and Aditi KulkarniBackgroundStandardization of Triphala Juice was performed by using the WHO Guidelines. The Parameters included Preliminary Analysis, Phytochemical Identification, Heavy Metal Estimation, etc. A new simple, specific, precise and accurate UV Spectrophotometric, High-Performance Liquid.MethodsChromatography and High-Performance Thin Layer Chromatography method has been developed for the Estimation of G Read More
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