Current Psychiatry Research and Reviews - Volume 20, Issue 2, 2024

Depression is a mental disorder that affects 279 million people. Patients with depression will not only have an impact on themselves but can also have an impact on others. Provide an overview of the impact of depression on health workers, workers, students and patients, as well as the prevention of depression. Data on the impact of depression and its prevention using the Google Scholar and Pubmed search engine. De Read More

Atypical antipsychotic quetiapine (QTP) exhibits high pharmacokinetic variability and population pharmacokinetic (PopPK) analysis is one of the approaches used to characterize factors influencing QTP pharmacokinetic variability. Though QTP is not regarded as a narrow therapeutic index drug, knowledge of this area is of importance. Thus, this review was conducted to summarize significant predictors for QTP pharmacoki Read More

Historically, formal thought disorder (FTD) has been considered one of the distinctive key symptoms of schizophrenia and is still regarded as an important early warning sign and a marker of illness severity with solid predictive value. Recent studies are able to found that the presence of FTD is predictive of the subsequent diagnosis of schizophrenia and often precedes the frank clinical picture by several months. Much effort h Read More

A large body of literature indicates that the novel coronavirus disease (COVI D-19) was, and still is, a stressful and traumatic experience for different groups of people. Exposure to unexpected deaths or fear of death increases the risk of developing post-traumatic stress disorder (PTSD) anxiety disorder. Understanding the relationship between PTSD and SARS-CoV- 2 infection can help reduce the risk of developing psychi Read More

Within a decade the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9 system), an advanced gene-editing technology became one of the celebrated approaches in modern disease therapeutics and was reported to have a potential role in the alteration of non-coding RNAs segment which are the pivotal causes behind the several mental disorder such as Schizophrenia. In general, Schizophrenia is refer Read More

Background: Borderline Personality Disorder (BPD) is a psychiatric condition that affects approximately 2% of the population worldwide. It can present many challenges and can therefore be difficult to treat successfully by mental health professionals. Aim: The aim of this systematic review was to detect whether repetitive Transcranial Magnetic Stimulation (rTMS) is an effective intervention for the management of BPD to the Read More

Introduction: Oxidative stress is an imbalance between an organism's reactive oxygen species (ROS) production and antioxidant defence capacity. Long-term oxidative stress contributes to cellular ageing and plays a role in the pathogenesis of several diseases. Several investigations indicated that oxidative stress has a role in the pathogenesis of ASD. Objectives: Present study was undertaken to record the association of GSTTT Read More

Parental stress and depression are factors that significantly affect the exercise of the parental role and have an impact on the upbringing of children and their quality of life. The purpose of this study is to investigate the differences between the dependent variables of quality of life, anxiety and depression in relation to the demographic characteristics, as an independent variable, in the entire sample before the imple Read More

Background: Healthcare workers (HCWs) who are directly involved in the management of patients with SARS-CoV-2 infection are at higher risk of psychological disorders. Objective: In this study, we evaluated the risk factors related to mental health disorders in HCWs active in the management of the COVID-19 pandemic in Mashhad, Iran. Methods: This was a cross-sectional investigation performed between April 2020 and May 2 Read More