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- ISSN: 1381-6128
- E-ISSN: 1873-4286
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Treatment of Severe Aplastic Anemia with Porcine Anti-Human Lymphocyte Globulin
- Source: Current Pharmaceutical Design, Volume 26, Issue 22, Jun 2020, p. 2661 - 2667
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- 01 Jun 2020
Abstract
Aplastic anemia (AA) is a bone marrow failure syndrome characterized by pancytopenia. Decreased numbers of hematopoietic stem cells and impaired bone marrow microenvironment caused by abnormal immune function describe the major pathogenesis of AA. Hematopoietic stem cell transplantation and immunesuppressive therapy are the first-line treatments for AA. Porcine anti-lymphocyte globulin (p-ALG) is a new product developed in China. Several studies have shown that p-ALG exhibited good therapeutic effects in AA.
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