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Volume 19, Issue 33
  • ISSN: 1381-6128
  • E-ISSN: 1873-4286

Abstract

Atherosclerosis is a chronic disease with a significant inflammatory component. Recent studies indicate a role of extracellular cyclophilins as contributors to endothelial inflammation and pathogenesis of atherosclerosis. In this article, we review current literature on pro-inflammatory activities of extracellular cyclophilins and discuss possible approaches to selectively target this novel proinflammatory factor.

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/content/journals/cpd/10.2174/1381612811319330009
2013-10-01
2025-04-21

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  • Article Type:     Research Article
Keyword(s): CD147; chemotaxis; Extracellular cyclophilins; inflammation; leukocytes; monocytes

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