Skip to content
2000
Volume 11, Issue 8
  • ISSN: 1381-6128
  • E-ISSN: 1873-4286

Abstract

Cytokines circulating in the blood affect CNS function through a variety of pathways. One of these pathways is by being transported directly across the blood-brain barrier (BBB). Transport of blood-borne cytokines across the BBB is now known to be an operational pathway by which cytokines can directly affect CNS functions. Cytokine transport across the BBB, however, is a complex event. Not all cytokines are transported and, for those which are, transport rates differ among cytokines, among brain regions, with physiological circumstances, and with disease. Here we address some of the major principles and concepts relating to cytokine transport and BBB function which have emerged as important to neuroimmunology and neuropathology.

Loading

Article metrics loading...

/content/journals/cpd/10.2174/1381612053381684
2005-03-01
2025-05-07
Loading full text...

Full text loading...

/content/journals/cpd/10.2174/1381612053381684
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test