Current Proteomics - Volume 20, Issue 1, 2023

Background: The advancement of proteomics studies leads to various benefits in research. However, in Malaysia, proteomics studies are still in their early stage. Objective: Four adult Pulchrana glandulosa individuals were collected from the stream of Temurun Waterfall for their proteomics information. Methods: These frogs’ skin secretions were collected, extracted, and analysed for their protein antimicrobial peptide comp Read More

Background: Leukocytes are key cellular effectors of inflammation in asthma and understanding their function in this disease is of crucial importance. Blood leukocytes reflect the actions of their counterparts in the lungs and they can be obtained through minimal invasive procedures as part of the peripheral blood. Objective: The aim of the study was to identify proteins in blood leukocyte proteomes that respond to ex Read More

Background: Such factors as diabetes and obesity can dramatically worsen COVID-19 symptoms. In addition, macrophage accumulation in adipose tissue is related to obesity. Therefore, macrophages play a significant role in raising COVID-19 susceptibility and severity in diabetes and obese patients. Methods: In this study, the functional impact of SARS-CoV-2 ORF7a on macrophages was analyzed using a domain-searching bi Read More

Background: Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, and it is a significant global health problem causing significant morbidity and mortality. Long noncoding RNAs (lncRNAs) have been identified as a class of gene expression regulators that play a critical role in the immune system. However, the function of lncRNAs in the immune microenvironment of ccRCC remains unclear. Methods: Th Read More

Background: Dental caries can affect the expression of salivary proteins. Proteomics allows us to analyze and identify many proteins in a single sample and experiment; bioinformatics is essential to analyze proteomic data. Objective: This research aims to identify and integrate the main differentially expressed proteins in the saliva of children with caries, infer their Gene Ontology and interactions, and identify regulatory f Read More

Background: S100 calcium-binding protein A11 (S100A11) has important roles in tumorigenesis and multiple cancer progression. Aims: In this study, we aimed to analyze the expression and prognostic value of S100A11 across cancers and further explore the relationship between S100A11 and the tumor immune microenvironment. Methods: We analyzed the differential expression of S100A11 in the TIMER, GEPIA, and BioGPS da Read More

Background: Despite the crucial involvement of vitronectin in affecting the perseverance of certain respiratory pathogens and the progression of several lung diseases, the association of vitronectin with tuberculosis (TB) has been poorly studied. The present study aimed to determine whether vitronectin levels are altered in TB patients compared to healthy humans. Methods: Twenty-four laboratory-confirmed tuberculosis patie Read More

Following the publication of the original article [1], the authors reported that the complete grant number of the funding was omitted. In this correction, the incorrect and correct grant numbers are mentioned. The original publication of this article has been corrected. The funding acknowledgement published previously is as follows: The study was funded by Fundamental Research Grant Scheme (FRGS) by the Minis Read More