Skip to content
2000
Volume 16, Issue 3
  • ISSN: 1570-1794
  • E-ISSN: 1875-6271

Abstract

The furo [2,3-b] indoline ring system is one of the most important structural units in various natural products. It has been known to have inherent biological activities and is utilized as a synthetic target for a number of natural compounds; therefore, this has contributed to a great demand for the growth of synthetic methods for this ring system. Most important compounds with furoindoline ring system are physovenine, madindoline A and B and makomotindoline etc. These compounds are well known to exhibit biological activity against different diseases such as glaucoma, cancer, cachexia, Castleman’s disease, rheumatoid arthritis, etc. The current article focuses on various synthetic approaches for furoindoline containing compounds and essential furoindoline moiety, such as oxindole-5-O-tetrahydropyranyl ether route etc., and various other diastereoand enantio- controlled approach in a very concise way.

Loading

Article metrics loading...

/content/journals/cos/10.2174/1570179416666190328211509
2019-05-01
2025-06-16
Loading full text...

Full text loading...

/content/journals/cos/10.2174/1570179416666190328211509
Loading

  • Article Type:
    Review Article
Keyword(s): alkaloid; cancer; chirality; Furoindole; fused heterocycle; natural product
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test