Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration.

Alkylboronate derivatives are important intermediates in organic synthesis and medicinal chemistry. The research of synthesizing alkylboronic acid derivatives has attracted great attention of chemists and many papers have reported various methods for preparing alkylboronates based on transition-metal-catalyzed hydroboration. In this review, we summarize the methods of synthesizing alkylboronate derivatives with different catalysts, such as Rhodium, Palladium, Copper, Iridium, Iron, Magnesiu, Platinum, Nickel and so on. Pinacolborane, bispinacolatodiboron and catecholborane are applied as important reagents and substrates with different skeleton structures and functional groups are employed to prepare diversity of alkylboronates.