Current Organic Chemistry - Volume 9, Issue 2, 2005

The photooxygenation of heterocycles represents a versatile and widely accepted tool for introducing oxygenated functions in a mild, simple and selective way. The review evidences the synthetic potential of the photooxygenation with particular attention to the reaction of Type II involving singlet oxygen in the first electronically excited state (1Δg), which has been applied to the most studied heterocycles as furans, thiophen Read More

New developments in the chemistry of quinoline derivatives are reviewed. Two general synthetic routes based on the utilization of mono-substituted or ortho-substituted anilines are discussed. Their major methods and modifications are analyzed.

Due to the potent biological activity exhibited by various indole derivatives, there is a continuous demand for novel synthetic procedures in this area. In 1989, the reaction of vinyl magnesium halides with ortho-substituted nitroarenes was discovered to lead to indoles. In the 1990s, it has attracted much attention, as it employs simple and readily available starting materials. This reaction is now frequently reported as the “ Read More

This review provides a comprehensive survey of the “one pot glycosylation” (OPG) strategy for the chemical synthesis of oligosaccharides, covering literatures from the first example reported by Kahne and Raghavan in 1993 through May 2003. The essence of the OPG is to distinguish the reactivity difference of a pair of the glycosylation donors or acceptors so as to carry out two glycosylation steps sequentially without puri Read More

Organic solvents are extensively used in organic synthesis and for this reason they are a matter of much concern due to characteristics such as: high flammability, volatility, hazardness, and toxicity. Thus the search for environmentally benign substitutes for organic solvents has recently gained more attention in view of the increasing importance of Green Chemistry. In this review, recent developments in the fields of supe Read More