Current Organic Chemistry - Volume 5, Issue 7, 2001

Development of new methodology for the preparation of enantiomerically pure compounds (EPCs) is at the forefront in the realm of synthetic chemistry in the 21st century. This is partly in response to the requirement for pharmaceuticals to be single entities. The preparation of both enantiomers of a target molecule is a challenging endeavor. Of a plethora of methodologies available for the preparation of EPCs, catal Read More

eta6-Arene ruthenium (II) complexes are versatile and potentially valuable synthetic Intermediates that have seen applications in diverse areas of organic chemistry. Though not as widely utilized as other arene metal complexes, arene ruthenium derivatives exhibit unique and useful reactivity patterns, and are typically easily handled air- and moisture-stable materials. This review summarizes the salient features of three comm Read More

Cobalt complexes are now used to mediate a host of organic reactions. This review Attempts to cover advances in this field, which have occurred in the last five years except where other reviews have been published more recently. In those cases where reviews have been published recently, the literature since the last review has been covered. Reaction coverage includes, but is not limited to Diels-Alder reactions, cobaloxime pi-c Read More

The chemistry of propargyldicobalt cations, also known as the Nicholas reaction, is Reviewed, with a focus on the developments since 1995. Advances in the understanding of the fundamental properties, such as structure, stability, and reactivity, of both the hexacarbonyl complexes and those bearing other ligands are discussed. All reactions involving propargyl cation dicobalt complexes are covered, including those stem Read More

The (4+3)cyclocoupling reaction of allyl cations to 1,3-dienes is an efficient and easy route for the stereoselective synthesis of seven-membered ring compounds. Annulations using these species have opened easy access to a wide range of organic frameworks that have been utilized in the synthesis of natural products, pharmacologically active compounds and key intermediates for various useful organic and alkaloid compounds.