Current Organic Chemistry - Volume 28, Issue 10, 2024

In recent times, many research groups have focused their attention on nitrogencontaining heterocyclic compounds with the aim of gaining a deeper understanding of their biological characteristics. Among them, molecules based on 1,2,3-triazole and benzimidazole have exhibited diverse biological applications and are present in many drug molecules. The purpose of this review is to describe various benzimidazole-1,2,3-tri Read More

The Nazarov reaction involves the cyclization of divinyl ketones into cyclopentenones under the influence of strong acids. The prevalence of five-membered carbocycles in a multitude of natural and bioactive products has triggered an intense development of efficient methods for their construction. In particular, asymmetric versions of the Nazarov reaction are achieved by using either a chiral auxiliary or a chiral catalys Read More

In this study, magnetic hercynite nanoparticles (FeAl2O4, MNPs) were functionalized by cheap and readily available tris(hydroxymethyl)aminomethane (Tris) as an organocatalyst. Various techniques, including Vibrating Sample Magnetometry (VSM), Energy Dispersive X-ray Spectroscopy (EDS), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Thermogravimetric Analysis (TG) Read More

Due to very good biological activity and use as fluorescent probes, coumarin synthesis and developing new synthesis methods are still an attractive area for many research groups. In this work, for the first time, a novel, mild, and green method has been developed for coumarin synthesis by using supercritical diethyl ether as a reaction medium. The optimum conditions for the synthesis of 3-acetylcoumarins and 4-methylcou Read More

A total of twelve pentacyclic triterpenoid derivatives based on betulin (1) and lupeol (2) scaffolds isolated from Diospyros foxworthyi were hemisynthesized by acylation or acetylation reactions with appropriate acid chloride or acetic anhydride. The structures of the hemisynthesised compounds were characterised by means of FT-IR, 1D- and 2D-NMR, as well as HRMS analysis. These compounds were assayed for in vi Read More