Current Organic Chemistry - Volume 21, Issue 7, 2017

The deoxygenation of tertiary phosphine oxides is an important reaction, as it provides useful intermediates and reagents, makes the available P-ligands useful in transition metal complexes, and regenerates wastes produced by the Wittig-, Mitsunobu and Appel reactions. Methods for the reduction of the P=O moiety comprising different metal and other hydrides, silanes and other species are surveyed, especially from the Read More

Ultrafast photoreactions play a key-role in numerous biological systems. They provide vision, phototaxis, UV-protection as well as energy storage and energy conversion with an efficiency which, so far, has not been reached under laboratory conditions. Detailed mechanistic studies can help to elucidate the underlying principles, but the systems of interest are often too large to be treated solely with accurate quantum methods. Read More

Coumarins are naturally occurring phytochemicals with heterocyclic structures which display a wide range of biological activities against neurological diseases such as Alzheimer´s disease (AD). This study reviews recent research into the design, synthesis and pharmacological profile of several series of synthetic coumarin ligands with clearcholinesterase, and assesses the monoamino oxidases (MAO-A and MAO-B) inhi Read More

Salts of various oniums such as ammonium, phosphonium, tellurium, arsonium, bismuthenium have been used as phase transfer catalyst in many oxidation reactions. These ions are also in use as carriers of anionic oxidants such as permanganate, chromate, dichromate, etc. Among these oniums, alkylammonium ions have been extensively studied. Alkylammonium ions are charged molecules, susceptible for acquiring hydr Read More

Background: Since introduction of chalcones in 1899, chalcones have been considered as precursors of flavones in the biosynthesis of flavonoids. However, because the chalcones include multi-functional groups on aromatic rings, developments of efficient synthetic methodologies as well as synthetic strategies involving protection/ deprotection should be considered. Objective: The primary objective of this study was to descri Read More