Current Organic Chemistry - Volume 21, Issue 26, 2017

Developing immunoassays for detecting natural and synthetic contaminants in foods and environments have raised great attention. Thus, tailoring the structure of the conjugates via hapten design has been regarded as an original and efficient way to obtain a high-quality antibody. To promote the development of this kind of antibodies and immunoassays, we first introduced three historic stages of hapten development: singleha Read More

Polycyclic aromatic hydrocarbons (PAHs) are a class of ubiquitous contaminants produced by natural or anthropogenic processes and found in various environment and food samples. A number of PAHs are carcinogenic and listed as priority pollutants in a variety of regulations. For a long time, much public attention has been drawn on PAHs due to the sensitive issue of environmental risks and food safety. In recent years, i Read More

Food-borne mycotoxins are now recognized as a major cause of food safety issue. Currently, a number of immunochemical methods have been applied to mycotoxin analysis because of their high specificity, facilitate sample preparation, and ease of use. These methods include widely applicable ELISAs, biosensors, and noninstrumental immunoassays. As a rule, immunoassay is based on specific interaction between ant Read More

Carbamate chemicals are N-substituted esters of the organic compound carbamic acid, which are widely used in the agrochemical industry as pesticides. Most carbamate pesticides are potentially hazardous for human health and thus their levels in food and the environment should be carefully monitored. Detection and quantification of carbamates are conventionally performed by high-performance liquid chromatogra Read More

Organophosphorus (OP) chemicals are mainly used as pesticides to control pests in both agricultural and domestic settings. The widespread and frequent use of OP pesticides has resulted in their presence as residues in environment and food. Due to their high toxicity and powerful inhibitors of cholinesterases, it is essential to monitor the residual OP chemicals in the environment and organism. Immunoassays for OP chemical Read More

Pyrethroids exist in numerous commercial insecticide formulations and have been used extensively all over the globe for pest control indoors and outdoors in many fields such as agriculture, public health, home use, and veterinary applications. The use of pyrethroids has increased continuously in recent years. This review aims to provide the latest research progress on newly developed haptens and antibodies, as well as their m Read More

Sulfonamide (SA) drugs are among the antimicrobial agents utilized for preventing and treating animal infections. Unfounded use of SA drugs may contribute to such problems as chemical residues in food and the environment. As a sensitive, selective and rapid method, the immunoassay has been investigated with varying parameters by numerous research groups for monitoring and determining sulfonamide residues. To unde Read More

Nitrofurans are a broad group of drugs once widely used for the treatment of microbial and protozoal infections in many livestock species. However, as concerns grew globally with regard to the potentially carcinogenic and mutagenic effects of their residues in foods, they have been banned from use in many parts of the world. In order to monitor compliance to these bans, it is essential to have fit-for-purpose testing Read More

Background: Calix[4]phyrins are fascinating hybrid molecules that contain a mixture of sp2- and sp3- hybridized meso-carbon bridges and bear analogy to both porphyrins and calix[4]pyrroles and hence find use in various applications. Various methods have been reported in the literature for the synthesis of calix [4] phyrins but with disadvantages of using corrosive acids and getting mixture of products, the separation of whic Read More